Compile Data Set for Download or QSAR
Report error Found 340 Enz. Inhib. hit(s) with all data for entry = 9425
TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465458BDBM465458(US10793568, Compound I-110)
Affinity DataEC50:  0.100nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465567BDBM465567(US10793568, Compound I-217)
Affinity DataEC50:  0.126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465447BDBM465447(US10793568, Compound I-101)
Affinity DataEC50:  0.158nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465515BDBM465515(US10793568, Compound I-164)
Affinity DataEC50:  0.200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465399BDBM465399(US10793568, Compound I-18)
Affinity DataEC50:  0.200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465473BDBM465473(US10793568, Compound I-124)
Affinity DataEC50:  0.200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465464BDBM465464(US10793568, Compound I-115)
Affinity DataEC50:  0.251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465576BDBM465576(US10793568, Compound I-226)
Affinity DataEC50:  0.251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465471BDBM465471(US10793568, Compound I-122)
Affinity DataEC50:  0.251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465575BDBM465575(US10793568, Compound I-225)
Affinity DataEC50:  0.316nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465460BDBM465460(US10793568, Compound I-112)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465457BDBM465457(US10793568, Compound I-109)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465453BDBM465453(US10793568, Compound I-105)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465521BDBM465521(US10793568, Compound I-170)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465487BDBM465487(US10793568, Compound I-135)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465452BDBM465452(US10793568, Compound I-104)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465566BDBM465566(US10793568, Compound I-216)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465563BDBM465563(US10793568, Compound I-213)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465459BDBM465459(US10793568, Compound I-111)
Affinity DataEC50:  0.501nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465477BDBM465477(US10793568, Compound I-127)
Affinity DataEC50:  0.501nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465562BDBM465562(US10793568, Compound I-212)
Affinity DataEC50:  0.631nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465636BDBM465636(US10793568, Compound I-287)
Affinity DataEC50:  0.631nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465524BDBM465524(US10793568, Compound I-173)
Affinity DataEC50:  0.631nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465538BDBM465538(US10793568, Compound I-187)
Affinity DataEC50:  0.631nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465504BDBM465504(US10793568, Compound I-153)
Affinity DataEC50:  0.631nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465601BDBM465601(US10793568, Compound I-251)
Affinity DataEC50:  0.794nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465456BDBM465456(US10793568, Compound I-108)
Affinity DataEC50:  0.794nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465491BDBM465491(US10793568, Compound I-140)
Affinity DataEC50:  0.794nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465544BDBM465544(US10793568, Compound I-194)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465683BDBM465683(US10793568, Compound I-334)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465393BDBM465393(US10793568, Compound I-12)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465604BDBM465604(US10793568, Compound I-254)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465553BDBM465553(US10793568, Compound I-203)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465633BDBM465633(US10793568, Compound I-284)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465646BDBM465646(US10793568, Compound I-297)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465678BDBM465678(US10793568, Compound I-329)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465692BDBM465692(US10793568, Compound I-343)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465488BDBM465488(US10793568, Compound I-136)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465687BDBM465687(US10793568, Compound I-338)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465634BDBM465634(US10793568, Compound I-285)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465409BDBM465409(US10793568, Compound I-28)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465536BDBM465536(US10793568, Compound I-185)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465537BDBM465537(US10793568, Compound I-186)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465501BDBM465501(US10793568, Compound I-150)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465533BDBM465533(US10793568, Compound I-182)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465545BDBM465545(US10793568, Compound I-195)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465609BDBM465609(US10793568, Compound I-260)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465571BDBM465571(US10793568, Compound I-221)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465724BDBM465724(US10793568, Compound I-54)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 465532BDBM465532(US10793568, Compound I-181)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

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