Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 9460
TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  1nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468290(US10800804, Example S11 | 3-{4-[(Butylamino)carbon...)
Affinity DataKd:  1nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468297(US10800804, Example 3b)
Affinity DataKd:  1nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  1nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468298(US10800804, Example 3c)
Affinity DataKd:  2nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468288(US10800804, Example S8b | 3′-Deoxy-3-O-[(5,6...)
Affinity DataKd:  2nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468296(US10800804, Example 3a | 3,3′-dideoxy-3,3...)
Affinity DataKd:  3nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468294(US10800804, Example S21 | 3,3′-Dideoxy-3-[4-...)
Affinity DataKd:  3nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468291(US10800804, Example S16 | 3,3′-Dideoxy-3R...)
Affinity DataKd:  7nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468287(US10800804, Example S8a | 3′-Deoxy-3-O-[(5,6...)
Affinity DataKd:  28nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  60nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  60nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468292(US10800804, Example S20a | 3-(9-anthracene carboxa...)
Affinity DataKd:  64nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468294(US10800804, Example S21 | 3,3′-Dideoxy-3-[4-...)
Affinity DataKd:  66nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468289(US10800804, Example S8c | 3′-{4-[(Butylamino...)
Affinity DataKd:  72nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468290(US10800804, Example S11 | 3-{4-[(Butylamino)carbon...)
Affinity DataKd:  77nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468296(US10800804, Example 3a | 3,3′-dideoxy-3,3...)
Affinity DataKd:  78nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468297(US10800804, Example 3b)
Affinity DataKd:  79nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468291(US10800804, Example S16 | 3,3′-Dideoxy-3R...)
Affinity DataKd:  90nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468298(US10800804, Example 3c)
Affinity DataKd:  110nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-3(Human)
TBA

US Patent
LigandPNGBDBM468293(US10800804, Example S20b)
Affinity DataKd:  140nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468287(US10800804, Example S8a | 3′-Deoxy-3-O-[(5,6...)
Affinity DataKd:  320nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468292(US10800804, Example S20a | 3-(9-anthracene carboxa...)
Affinity DataKd:  380nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468288(US10800804, Example S8b | 3′-Deoxy-3-O-[(5,6...)
Affinity DataKd:  480nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468293(US10800804, Example S20b)
Affinity DataKd:  490nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
TBA

US Patent
LigandPNGBDBM468289(US10800804, Example S8c | 3′-{4-[(Butylamino...)
Affinity DataKd:  1.20E+3nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent