Compile Data Set for Download or QSAR
Report error Found 141 Enz. Inhib. hit(s) with all data for entry = 9653
TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478951(2-(6-(1-acryloyl-2,5-dihydro-1H-pyrrol-3-yl)pyridi...)
Affinity DataIC50: 0.900nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478782(US10894786, Comp. No 36 | US10894786, Comp. No 37 ...)
Affinity DataIC50: 3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478952((E)-2-(1'-(but-2-enoyl)-1',2',5',6'-tetrahydro-[2,...)
Affinity DataIC50: 3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478281(2-(1'-acryloyl-1',2',3',6'-tetrahydro-[2,4'-bipyri...)
Affinity DataIC50: 3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478960(2-(1'-cyano-1',2',3',6'-tetrahydro-[2,4'-bipyridin...)
Affinity DataIC50: 4nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478947(2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyri...)
Affinity DataIC50: 4nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478422((S)-2-(4-(1-acryloyl-1,2,5,6-tetrahydropyridin-3-y...)
Affinity DataIC50: 4.30nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478485((S)-2-(4-(1-acryloyl-1,2,3,6-tetrahydropyridin-4-y...)
Affinity DataIC50: 5nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478954(2-(1'-(but-2-ynoyl)-1',2',5',6'-tetrahydro-[2,3'-b...)
Affinity DataIC50: 5nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478942(US10894786, Comp. No 44 | US10894786, Comp. No 45 ...)
Affinity DataIC50: 5.80nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478959(2-(1'-cyano-1',2',5',6'-tetrahydro-[2,3'-bipyridin...)
Affinity DataIC50: 6nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478326(US10894786, Comp. No 6 | 2-(1''-acryloyl-1'',2'',3...)
Affinity DataIC50: 6nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478934(2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyri...)
Affinity DataIC50: 6nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478946(2-(6-(1-acryloylpyrrolidin-3-yl)pyridin-3-yl)-N-(5...)
Affinity DataIC50: 6nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478944(US10894786, Comp. No 46 | US10894786, Comp. No 47 ...)
Affinity DataIC50: 6nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478944(US10894786, Comp. No 46 | US10894786, Comp. No 47 ...)
Affinity DataIC50: 6.90nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478328((S)-2-(4-(1-acryloylpiperidin-4-yl)phenyl)-N-(5-cy...)
Affinity DataIC50: 7nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478948(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(1'-propioloyl...)
Affinity DataIC50: 7nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478942(US10894786, Comp. No 44 | US10894786, Comp. No 45 ...)
Affinity DataIC50: 9nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478951(2-(6-(1-acryloyl-2,5-dihydro-1H-pyrrol-3-yl)pyridi...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478955(N-(5-cyclopropy1-1H-pyrazol-3-yl)-2-(1'-methacrylo...)
Affinity DataIC50: 10nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478758(2-(4-(4-acryloylpiperazin-1-yl)phenyl)-N-(5-cyclop...)
Affinity DataIC50: 11.7nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478958(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(6-(1-propiolo...)
Affinity DataIC50: 12nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478430(2-(4-(1-acryloyl-1,2,3,6-tetrahydropyridin-4-yl)ph...)
Affinity DataIC50: 12nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478948(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(1'-propioloyl...)
Affinity DataIC50: 12nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478940(2-(4-(1-acryloyl-1,2,5,6-tetrahydropyridin-3-yl)-3...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478327(N-(4-(4-(1-((5-cyclopropyl-1H-pyrazol-3-yl)amino)-...)
Affinity DataIC50: 18nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478350((S,E)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(4-(1-(4...)
Affinity DataIC50: 18.8nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478489(N-(4'-(1 ((5-cyclopropyl-1H-pyrazol-3-yl)amino)-1-...)
Affinity DataIC50: 19nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478950(2-(1'-(but-2-ynoyl)-1',2',5',6'-tetrahydro-[2,3'-b...)
Affinity DataIC50: 19nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478957(2-(1'-acryloyl-1',2',3',6'-tetrahydro-[2,4'-bipyri...)
Affinity DataIC50: 19nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478491(2-(4-(1-acryloyl-2,3,6,7-tetrahydro-1H-azepin-4-yl...)
Affinity DataIC50: 21nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478947(2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyri...)
Affinity DataIC50: 23nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478422((S)-2-(4-(1-acryloyl-1,2,5,6-tetrahydropyridin-3-y...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478360(N-(1-(4-(1-((5-cyclopropyl-1H-pyrazol-3-yl)amino)-...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478354(2-(6-(4-acryloylpiperazin-1-yl)pyridin-3-yl)-N-(5-...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478351((S,E)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(4-(1-(4...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478949(2-(1'-(but-2-ynoyl)-1',2',3',6'-tetrahydro-[2,4'-b...)
Affinity DataIC50: 25nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478350((S,E)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(4-(1-(4...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478330((S,E)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(4-(1-(4...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478329(2-(6-(1-acryloylpiperidin-4-yl)pyridin-3-yl)-N-(5-...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478328((S)-2-(4-(1-acryloylpiperidin-4-yl)phenyl)-N-(5-cy...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478327(N-(4-(4-(1-((5-cyclopropyl-1H-pyrazol-3-yl)amino)-...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478326(US10894786, Comp. No 6 | 2-(1''-acryloyl-1'',2'',3...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478281(2-(1'-acryloyl-1',2',3',6'-tetrahydro-[2,4'-bipyri...)
Affinity DataKd: <25nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478329(2-(6-(1-acryloylpiperidin-4-yl)pyridin-3-yl)-N-(5-...)
Affinity DataIC50: 28nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478782(US10894786, Comp. No 36 | US10894786, Comp. No 37 ...)
Affinity DataIC50: 29nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478939(2-(6-(1-acryloylpiperidin-3-yl)pyridin-3-yl)-N-(5-...)
Affinity DataIC50: 29nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478934(2-(1'-acryloyl-1',2',5',6'-tetrahydro-[2,3'-bipyri...)
Affinity DataIC50: 30nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478944(US10894786, Comp. No 46 | US10894786, Comp. No 47 ...)
Affinity DataIC50: 32nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

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