Compile Data Set for Download or QSAR
Report error Found 453 Enz. Inhib. hit(s) with all data for entry = 9827
TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491967BDBM491967(US10975068, Example 108 | (S)—N-(2-Hydroxy-2-...)
Affinity DataKd:  0.0700nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491901BDBM491901(US10975068, Example 39 | 5-(6-(((S)-1-Cyclopropyle...)
Affinity DataKd:  0.120nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492041BDBM492041(US10975068, Example 182 | 4-((S)-4,4-Difluoro-2-me...)
Affinity DataKd:  0.120nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491879BDBM491879(US10975068, Example 17 | (S)-5-(6-(Cyclohexylamino...)
Affinity DataKd:  0.150nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491893BDBM491893(US10975068, Example 31 | 5-(6-(((R*)-2,2-Difluoroc...)
Affinity DataKd:  0.150nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491954BDBM491954(US10975068, Example 95 | (S)-5-(4-(Difluoromethyl)...)
Affinity DataKd:  0.150nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492210BDBM492210(5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyrid...)
Affinity DataKd:  0.150nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491945BDBM491945(US10975068, Example 86 | (S)—N-(2-Hydroxy-2-m...)
Affinity DataKd:  0.170nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491940BDBM491940(US10975068, Example 81 | (S)—N-(2-Hydroxy-2-m...)
Affinity DataKd:  0.170nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491890BDBM491890(US10975068, Example 28 | (S)-5-(6-(Cyclopentylamin...)
Affinity DataKd:  0.170nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492045BDBM492045(US10975068, Example 186 | 4-((S)-4,4-Difluoro-2-me...)
Affinity DataKd:  0.180nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492284BDBM492284(4-[(2S)-4,4-Difluoro-2-methyl-pyrrolidine-1-carbon...)
Affinity DataKd:  0.180nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491947BDBM491947(US10975068, Example 88 | (S)-5-(6-((2-Cyclopropylp...)
Affinity DataKd:  0.190nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491939BDBM491939(US10975068, Example 80 | (S)-5-(6-(tert-Butylamino...)
Affinity DataKd:  0.190nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491971BDBM491971(US10975068, Example 112 | N-(2-Hydroxy-2-methylpro...)
Affinity DataKd:  0.200nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492278BDBM492278(4-[(2S)-4,4-Difluoro-2-methyl-pyrrolidine-1-carbon...)
Affinity DataKd:  0.210nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492042BDBM492042(US10975068, Example 183 | 4-((S)-4,4-Difluoro-2-me...)
Affinity DataKd:  0.220nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491934BDBM491934(US10975068, Example 75 | (S)-5-(6-(Cyclohexylamino...)
Affinity DataKd:  0.230nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492044BDBM492044(US10975068, Example 185 | 4-((S)-4,4-Difluoro-2-me...)
Affinity DataKd:  0.230nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492283BDBM492283(4-[(2S)-4,4-Difluoro-2-methyl-pyrrolidine-1-carbon...)
Affinity DataKd:  0.230nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492113BDBM492113(5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyrid...)
Affinity DataKd:  0.25nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491867BDBM491867(US10975068, Example 5 | (S)-5-(6-(Cyclohexylamino)...)
Affinity DataKd:  0.25nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491966BDBM491966(US10975068, Example 107 | (S)-5-(6-((2-Cyclopropyl...)
Affinity DataKd:  0.260nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491962BDBM491962(US10975068, Example 103 | (S)-4-(4,4-Difluoro-2-me...)
Affinity DataKd:  0.260nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491894BDBM491894(US10975068, Example 32 | 5-(6-(((S*)-2,2-Difluoroc...)
Affinity DataKd:  0.260nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492298BDBM492298(4-((1s,4s)-7-Azabicyclo[2.2.1]heptane-7-carbonyl)-...)
Affinity DataKd:  0.270nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492106BDBM492106(5-[4-(Difluoromethyl)-6-[[(1S)-1-(trifluoromethyl)...)
Affinity DataKd:  0.280nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491896BDBM491896(US10975068, Example 34 | (S)-5-(6-(Cyclohexylamino...)
Affinity DataKd:  0.290nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492310BDBM492310(US10975068, Example 451)
Affinity DataKd:  0.290nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492187BDBM492187((S)-4-(4,4-Difluoro-2-methylpyrrolidine-1-carbonyl...)
Affinity DataKd:  0.310nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491935BDBM491935(US10975068, Example 76 | (S)-5-(6-(Cyclohexylamino...)
Affinity DataKd:  0.340nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491918BDBM491918(US10975068, Example 56 | (S)-5-(6-((2-Cyclopropylp...)
Affinity DataKd:  0.340nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491953BDBM491953(US10975068, Example 94 | (S)-4-(4,4-Difluoro-2-met...)
Affinity DataKd:  0.360nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492290BDBM492290(5-[6-(tert-Butylamino)-4-(difluoromethyl)-3-pyridy...)
Affinity DataKd:  0.360nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492285BDBM492285(4-[(2S)-4,4-Difluoro-2-methyl-pyrrolidine-1-carbon...)
Affinity DataKd:  0.370nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492220BDBM492220(5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyrid...)
Affinity DataKd:  0.370nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492206BDBM492206(5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyrid...)
Affinity DataKd:  0.380nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491959BDBM491959(US10975068, Example 100 | (S)-4-(4,4-Difluoro-2-me...)
Affinity DataKd:  0.390nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491991BDBM491991(US10975068, Example 132 | (S)—N-(2-Hydroxy-2-...)
Affinity DataKd:  0.410nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491957BDBM491957(US10975068, Example 98 | 4-((1s,4s)-7-Azabicyclo[2...)
Affinity DataKd:  0.410nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491977BDBM491977(US10975068, Example 118 | (S)-4-(4,4-Difluoro-2-me...)
Affinity DataKd:  0.430nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491895BDBM491895(US10975068, Example 33 | N-(2-Hydroxy-2-methylprop...)
Affinity DataKd:  0.430nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492054BDBM492054(US10975068, Example 195 | 4-((S)-4,4-Difluoro-2-me...)
Affinity DataKd:  0.430nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492275BDBM492275(4-[(2S)-4,4-Difluoro-2-methyl-pyrrolidine-1-carbon...)
Affinity DataKd:  0.430nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492296BDBM492296(4-((1s,4s)-7-Azabicyclo[2.2.1]heptane-7-carbonyl)-...)
Affinity DataKd:  0.440nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492300BDBM492300(4-((1s,4s)-7-Azabicyclo[2.2.1]heptane-7-carbonyl)-...)
Affinity DataKd:  0.470nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491973BDBM491973(US10975068, Example 114 | (S)-5-(4-(Difluoromethyl...)
Affinity DataKd:  0.490nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492155BDBM492155((S)-5-(4-Difluoromethyl)-6-((4,4,4-trifluoro-2-met...)
Affinity DataKd:  0.5nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 491909BDBM491909(US10975068, Example 47 | N-(2-Hydroxy-2-methylprop...)
Affinity DataKd:  0.5nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 492132BDBM492132(4-[(2S)-4,4-Difluoro-2-methyl-pyrrolidine-1-carbon...)
Affinity DataKd:  0.510nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

Displayed 1 to 50 (of 453 total ) | Next | Last >>
Jump to: