Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 10042
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  135nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM510514(US11077128, Compound BisAcDcB)
Affinity DataKi:  395nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM510514(US11077128, Compound BisAcDcB)
Affinity DataKi:  1.18E+3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM510515(US11077128, Compound TrisAcDcB)
Affinity DataKi:  2.50E+3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM510515(US11077128, Compound TrisAcDcB)
Affinity DataKi:  1.32E+4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent