Compile Data Set for Download or QSAR
Report error Found 431 Enz. Inhib. hit(s) with all data for entry = 527
TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41656BDBM41656(US11116760, Example 414)
Affinity DataEC50:  0.0480nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41647BDBM41647(US11116760, Example 408)
Affinity DataEC50:  0.0490nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41690BDBM41690(US11116760, Example 439)
Affinity DataEC50:  0.0490nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41636BDBM41636(US11116760, Example 356)
Affinity DataEC50:  0.0500nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41649BDBM41649(US11116760, Example 410)
Affinity DataEC50:  0.0540nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41651BDBM41651(US11116760, Example 411)
Affinity DataEC50:  0.0600nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41683BDBM41683(US11116760, Example 433)
Affinity DataEC50:  0.0760nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41687BDBM41687(US11116760, Example 436)
Affinity DataEC50:  0.0760nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41642BDBM41642(US11116760, Example 406)
Affinity DataEC50:  0.0800nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41671BDBM41671(US11116760, Example 423)
Affinity DataEC50:  0.0800nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41709BDBM41709(US11116760, Example 458)
Affinity DataEC50:  0.0900nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41657BDBM41657(US11116760, Example 415)
Affinity DataEC50:  0.0910nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41652BDBM41652(US11116760, Example 412)
Affinity DataEC50:  0.0910nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41700BDBM41700(US11116760, Example 449)
Affinity DataEC50:  0.0920nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41712BDBM41712(US11116760, Example 461)
Affinity DataEC50:  0.0930nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41681BDBM41681(US11116760, Example 431)
Affinity DataEC50:  0.0940nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41675BDBM41675(US11116760, Example 426)
Affinity DataEC50:  0.0960nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41637BDBM41637(US11116760, Example 399)
Affinity DataEC50:  0.100nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41638BDBM41638(US11116760, Example 401)
Affinity DataEC50:  0.100nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 28964BDBM28964(US11116760, Example 141)
Affinity DataEC50:  0.100nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41639BDBM41639(US11116760, Example 402)
Affinity DataEC50:  0.100nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41640BDBM41640(US11116760, Example 404)
Affinity DataEC50:  0.100nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 28931BDBM28931(US11116760, Example 111)
Affinity DataEC50:  0.100nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41713BDBM41713(US11116760, Example 462)
Affinity DataEC50:  0.102nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41720BDBM41720(US11116760, Example 469)
Affinity DataEC50:  0.103nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41684BDBM41684(US11116760, Example 434)
Affinity DataEC50:  0.103nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41662BDBM41662(US11116760, Example 418)
Affinity DataEC50:  0.104nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41682BDBM41682(US11116760, Example 432)
Affinity DataEC50:  0.110nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41725BDBM41725(US11116760, Example 474)
Affinity DataEC50:  0.112nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41728BDBM41728(US11116760, Example 477)
Affinity DataEC50:  0.115nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41664BDBM41664(US11116760, Example 420)
Affinity DataEC50:  0.116nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41659BDBM41659(US11116760, Example 417)
Affinity DataEC50:  0.117nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41658BDBM41658(US11116760, Example 416)
Affinity DataEC50:  0.126nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41715BDBM41715(US11116760, Example 464)
Affinity DataEC50:  0.130nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41705BDBM41705(US11116760, Example 454)
Affinity DataEC50:  0.140nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41736BDBM41736(US11116760, Example 484)
Affinity DataEC50:  0.143nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41711BDBM41711(US11116760, Example 460)
Affinity DataEC50:  0.150nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41673BDBM41673(US11116760, Example 424)
Affinity DataEC50:  0.150nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41726BDBM41726(US11116760, Example 475)
Affinity DataEC50:  0.157nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41695BDBM41695(US11116760, Example 444)
Affinity DataEC50:  0.161nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41679BDBM41679(US11116760, Example 429)
Affinity DataEC50:  0.162nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41644BDBM41644(US11116760, Example 407)
Affinity DataEC50:  0.162nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41722BDBM41722(US11116760, Example 471)
Affinity DataEC50:  0.179nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41678BDBM41678(US11116760, Example 428)
Affinity DataEC50:  0.180nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41721BDBM41721(US11116760, Example 470)
Affinity DataEC50:  0.181nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41674BDBM41674(US11116760, Example 425)
Affinity DataEC50:  0.185nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41719BDBM41719(US11116760, Example 468)
Affinity DataEC50:  0.189nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41666BDBM41666(US11116760, Example 421)
Affinity DataEC50:  0.191nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 41724BDBM41724(US11116760, Example 473)
Affinity DataEC50:  0.196nMAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 28957BDBM28957(US11116760, Example 136)
Affinity DataEC50:  0.200nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

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