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Found 26 Enz. Inhib. hit(s) with all data for entry = 10390
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532446((1aS,5aS)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataKi:  1.45nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532448((1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataKi:  3.80nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM388465((1aR,5aR)-2-(Tetrahydro-pyran-4-ylmethyl)-1a,2,5,5...)
Affinity DataKi:  58.7nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM388461((1aS,5aS)-2-(2,4-Difluoro-phenyl)-1a,2,5,5a-tetrah...)
Affinity DataKi:  97.6nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532445((1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataKi:  97.7nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532446((1aS,5aS)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataKi:  105nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM388461((1aS,5aS)-2-(2,4-Difluoro-phenyl)-1a,2,5,5a-tetrah...)
Affinity DataKi:  207nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM388465((1aR,5aR)-2-(Tetrahydro-pyran-4-ylmethyl)-1a,2,5,5...)
Affinity DataKi:  568nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532448((1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataKi:  1.20E+3nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50040979(CHEMBL3354966 | US11214548, Compound 408)
Affinity DataEC50:  75.8nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532437(US11214548, Compound 632)
Affinity DataEC50:  0.966nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532438(US11214548, Compound 634)
Affinity DataEC50:  1.10nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532438(US11214548, Compound 634)
Affinity DataEC50:  0.170nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532439(US11214548, Compound 631)
Affinity DataEC50:  108nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532440(US11214548, Compound 633)
Affinity DataEC50:  3.20nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532441(US11214548, Compound 673)
Affinity DataEC50:  1.01E+3nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50040979(CHEMBL3354966 | US11214548, Compound 408)
Affinity DataEC50:  2.69E+4nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532435(US11214548, Compound 368)
Affinity DataEC50:  35nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532435(US11214548, Compound 368)
Affinity DataEC50:  354nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532434(US11214548, Compound 340)
Affinity DataEC50:  6.28nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532433(US11214548, Compound 332)
Affinity DataEC50:  2nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50040970(CHEMBL3354975 | US11214548, Compound 269)
Affinity DataEC50:  809nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532443((1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataEC50:  1.10nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532443((1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahy...)
Affinity DataEC50:  251nMAssay Description:Table B: HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532441(US11214548, Compound 673)
Affinity DataEC50:  0.644nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM532442(US11214548, Compound 711 | {[(1aR,5aR)-2-(4-Oxy-py...)
Affinity DataEC50:  28.1nMAssay Description:Table D: Radioligand binding assays for human CB2 receptors were performed using two different agonist radioligands, [3H]CP55,940 and [3H]WIN55,212-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent