Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 10462
TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402321BDBM402321(US10329286, Example 2 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  2.60nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402333BDBM402333(US10329286, Example 6 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  3.10nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402340BDBM402340(US10329286, Example 10 | 6-(3-(2-chloro-4-((5- cyc...)
Affinity DataEC50:  3.40nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402341BDBM402341(US10329286, Example 11 | 6-(3-(2-chloro-4-((4- cyc...)
Affinity DataEC50:  3.80nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402327BDBM402327(US10329286, Example 4 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  3.90nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402326BDBM402326(US10329286, Example 3 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  4.40nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402332BDBM402332(US10329286, Example 5 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  4.80nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402305BDBM402305(US10329286, Example 1 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  6.10nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402334BDBM402334(US10329286, Example 7 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  8.5nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402336BDBM402336(US10329286, Example 8 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  15nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 402337BDBM402337(US10329286, Example 9 | 6-(3-(2-chloro-4-((5- cycl...)
Affinity DataEC50:  57nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent