Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 10771
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566614(3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy-1- met...)
Affinity DataEC50:  13nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566630(3-fluoro-5-(((1R,2R,2aS)-1,2,3,3,4,4-hexafluoro- 2...)
Affinity DataEC50:  11nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566616(3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a- hy...)
Affinity DataEC50:  6nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566617(3-fluoro-5-(((1R,2aR)-1,3,3,4,4-pentafluoro-2a- hy...)
Affinity DataEC50:  2.10E+3nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566618(1,3,3,4,4-pentafluoro-7-((5-fluoropyridin-3- yl)ox...)
Affinity DataEC50:  320nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566619(3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy- 2,2a,...)
Affinity DataEC50:  170nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566620(3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy-1- met...)
Affinity DataEC50:  410nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566621(3-fluoro-5-((3,3,4,4-tetrafluoro-1,2a-dihydroxy-1-...)
Affinity DataEC50: >5.00E+3nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566622(3-fluoro-5-((1,3,3,4,4-pentafluoro-2a-hydroxy-1- m...)
Affinity DataEC50:  100nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566623(3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy- 2,2a,...)
Affinity DataEC50:  330nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566624(3-((2a-amino-1,3,3,4,4-pentafluoro-2,2a,3,4- tetra...)
Affinity DataEC50:  630nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566625(3-fluoro-5-((1,1,2a,3,3,4,4-heptafluoro-2,2a,3,4- ...)
Affinity DataEC50: >5.00E+3nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566626(3-fluoro-5-((1,3,3-trifluoro-2a-hydroxy-2,2a,3,4- ...)
Affinity DataEC50:  4.10E+3nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566616(3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a- hy...)
Affinity DataEC50:  6nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566628((R)-3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy-1-...)
Affinity DataEC50:  7nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566629(3-fluoro-5-(((1R,2S,2aS)-1,2,3,3,4,4-hexafluoro- 2...)
Affinity DataEC50:  2nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM566615(3-fluoro-5-((1,3,3,4,4-pentafluoro-2a-hydroxy- 2,2...)
Affinity DataEC50:  10nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent