Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with all data for entry = 10841
LigandChemical structure of BindingDB Monomer ID 573147BDBM573147(US11453673, Example 9)
Affinity DataIC50: 0.958nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573138BDBM573138(US11453673, Example 4)
Affinity DataIC50: 1.06nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573155BDBM573155(US11453673, Example 16)
Affinity DataIC50: 1.20nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573136BDBM573136(US11453673, Example 3)
Affinity DataIC50: 1.26nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573154BDBM573154(US11453673, Example 15)
Affinity DataIC50: 1.40nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573144BDBM573144(US11453673, Example 6)
Affinity DataIC50: 1.88nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573148BDBM573148(US11453673, Example 10)
Affinity DataIC50: 2nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573139BDBM573139(US11453673, Example 5)
Affinity DataIC50: 2.70nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573135BDBM573135(US11453673, Example 2)
Affinity DataIC50: 2.81nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573154BDBM573154(US11453673, Example 15)
Affinity DataIC50: 3.10nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573138BDBM573138(US11453673, Example 4)
Affinity DataIC50: 3.65nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573138BDBM573138(US11453673, Example 4)
Affinity DataIC50: 3.71nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573135BDBM573135(US11453673, Example 2)
Affinity DataIC50: 3.73nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573147BDBM573147(US11453673, Example 9)
Affinity DataIC50: 3.73nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573135BDBM573135(US11453673, Example 2)
Affinity DataIC50: 4.11nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573149BDBM573149(US11453673, Example 11)
Affinity DataIC50: 4.77nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573154BDBM573154(US11453673, Example 15)
Affinity DataIC50: 4.90nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573147BDBM573147(US11453673, Example 9)
Affinity DataIC50: 4.94nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573144BDBM573144(US11453673, Example 6)
Affinity DataIC50: 5.98nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573152BDBM573152(US11453673, Example 13)
Affinity DataIC50: 6.35nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573155BDBM573155(US11453673, Example 16)
Affinity DataIC50: 6.54nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573148BDBM573148(US11453673, Example 10)
Affinity DataIC50: 6.72nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573144BDBM573144(US11453673, Example 6)
Affinity DataIC50: 7.03nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573145BDBM573145(US11453673, Example 7)
Affinity DataIC50: 7.76nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573155BDBM573155(US11453673, Example 16)
Affinity DataIC50: 8.67nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573136BDBM573136(US11453673, Example 3)
Affinity DataIC50: 9.36nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573146BDBM573146(US11453673, Example 8)
Affinity DataIC50: 10.1nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573148BDBM573148(US11453673, Example 10)
Affinity DataIC50: 10.6nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573136BDBM573136(US11453673, Example 3)
Affinity DataIC50: 11nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573139BDBM573139(US11453673, Example 5)
Affinity DataIC50: 11.1nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573139BDBM573139(US11453673, Example 5)
Affinity DataIC50: 11.5nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573134BDBM573134(US11453673, Example 1)
Affinity DataIC50: 12nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573149BDBM573149(US11453673, Example 11)
Affinity DataIC50: 13.2nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573150BDBM573150(US11453673, Example 12)
Affinity DataIC50: 13.2nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573149BDBM573149(US11453673, Example 11)
Affinity DataIC50: 17.6nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573134BDBM573134(US11453673, Example 1)
Affinity DataIC50: 20.3nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573152BDBM573152(US11453673, Example 13)
Affinity DataIC50: 21.8nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573152BDBM573152(US11453673, Example 13)
Affinity DataIC50: 21.8nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573153BDBM573153(US11453673, Example 14)
Affinity DataIC50: 22.3nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573146BDBM573146(US11453673, Example 8)
Affinity DataIC50: 25.4nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573145BDBM573145(US11453673, Example 7)
Affinity DataIC50: 28.5nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573134BDBM573134(US11453673, Example 1)
Affinity DataIC50: 29.4nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573145BDBM573145(US11453673, Example 7)
Affinity DataIC50: 32.7nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573150BDBM573150(US11453673, Example 12)
Affinity DataIC50: 33.9nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573146BDBM573146(US11453673, Example 8)
Affinity DataIC50: 36.9nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573150BDBM573150(US11453673, Example 12)
Affinity DataIC50: 44.6nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573153BDBM573153(US11453673, Example 14)
Affinity DataIC50: 48nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573153BDBM573153(US11453673, Example 14)
Affinity DataIC50: 52.4nMAssay Description:TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573146BDBM573146(US11453673, Example 8)
Affinity DataIC50: 2.66E+3nMAssay Description:Table 7: The following phosphodiesterase activities are measured using [3H]cGMP as reaction substrate: human PDE6A/6B. The catalytic active form of h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Eli Lilly

US Patent
LigandChemical structure of BindingDB Monomer ID 573134BDBM573134(US11453673, Example 1)
Affinity DataIC50: 5.59E+3nMAssay Description:Table 6: The following PDE activities are measured using [3H]cAMP as reaction substrate: human PDE3A (catalytic domain) and human PDE4D. Both enzymes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

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