Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 664
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.00100nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633253(US11458151, Compound 3 | Preparation of N [(R)-3-D...)
Affinity DataEC50:  0.0110nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633252(US11458151, Compound 2 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  0.0180nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.0580nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.124nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.251nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633255(US11458151, Compound MPL | Monophosphoryl Lipid A ...)
Affinity DataEC50:  0.258nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633253(US11458151, Compound 3 | Preparation of N [(R)-3-D...)
Affinity DataEC50:  0.462nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.780nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  1.32nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  1.39nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633256(US11458151, Compound 5 | Preparation of N [(R)-3-D...)
Affinity DataEC50:  2.90nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633255(US11458151, Compound MPL | Monophosphoryl Lipid A ...)
Affinity DataEC50:  3.10nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633253(US11458151, Compound 3 | Preparation of N [(R)-3-D...)
Affinity DataEC50:  3.95nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633259(US11458151, Compound 8 | Preparation of 2-[(R)-3-(...)
Affinity DataEC50:  4.99nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633252(US11458151, Compound 2 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  5.89nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  10.2nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  13.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633260(US11458151, Compound 9 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  15.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  19.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633252(US11458151, Compound 2 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  41nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633252(US11458151, Compound 2 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  64nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633255(US11458151, Compound MPL | Monophosphoryl Lipid A ...)
Affinity DataEC50:  152nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent