Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 10865
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575655BDBM575655(US11459340, Compound 37 | (S)-(6-((2-amino-3-chlor...)
Affinity DataIC50: 0.600nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575622BDBM575622(US11459340, Compound 1 | (6-((2-amino-3-chloropyri...)
Affinity DataIC50: 0.900nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479328BDBM479328((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 2nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479312BDBM479312(US10894797, Compound 1 | (3-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 3nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575630BDBM575630(US11459340, Compound 9 | (3S,4S)-8-(5-((6-amino-2,...)
Affinity DataIC50: 3nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575653BDBM575653(US11459340, Compound 35 | (6-((2-amino-3-chloropyr...)
Affinity DataIC50: 3nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575657BDBM575657(US11459340, Compound 39 | 3-((5-((3S,4S)-4-amino-3...)
Affinity DataIC50: 3.5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479312BDBM479312(US10894797, Compound 1 | (3-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 4nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575658BDBM575658(US11459340, Compound 40 | 3-((5-((3S,4S)-4-amino-3...)
Affinity DataIC50: 4.80nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479315BDBM479315((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575656BDBM575656(US11459340, Compound 38 | of (3-((3S,4S)-4-amino-3...)
Affinity DataIC50: 5.5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479333BDBM479333((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479317BDBM479317((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479318BDBM479318((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575626BDBM575626(US11459340, Compound 5 | (3S,4S)-8-(5-((2,3-dichlo...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479316BDBM479316((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479334BDBM479334((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479319BDBM479319((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2oxa-8- a...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479320BDBM479320((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479335BDBM479335((6-(((6aS,8S)-8-(1H-pyrazol-1-yl)-6a,7,8,9-tetrahy...)
Affinity DataIC50: 10nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479321BDBM479321((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 10nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479331BDBM479331((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 11nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479336BDBM479336((6-(((6aS,84R)-8-(1H-pyrazol-1-yl)-6a,7,8,9-tetrah...)
Affinity DataIC50: 11nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479323BDBM479323((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azasprio[4.5...)
Affinity DataIC50: 12nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575623BDBM575623(US11459340, Compound 2 | (3S,4S)-8-(5-((2-amino-3-...)
Affinity DataIC50: 12nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479332BDBM479332((3-((3S,4S)-4-amino-3-methyl-2-oxa- 8-azaspiro[4.5...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575629BDBM575629(US11459340, Compound 8 | (3S,4S)-8-(5-((3-chloro-2...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479314BDBM479314((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575624BDBM575624(US11459340, Compound 3 | 6-((2-amino-3-chloropyrid...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575625BDBM575625(US11459340, Compound 4 | (3S,4S)-8-(5-((2-amino-3-...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479322BDBM479322((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 14nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575628BDBM575628(US11459340, Compound 7 | (3S,4S)-8-(5-((3-chloro-2...)
Affinity DataIC50: 18nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575631BDBM575631(US11459340, Compound 10 | (3S,4S)-8-(5-((3-chloro-...)
Affinity DataIC50: 21nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479329BDBM479329((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 21nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479337BDBM479337((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 23nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575627BDBM575627(US11459340, Compound 6 | (3S,4S)-3-methyl-8-(3-(me...)
Affinity DataIC50: 85nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575654BDBM575654(US11459340, Compound 36 | 13-amino-10-(5-((2-amino...)
Affinity DataIC50: 269nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent