Compile Data Set for Download or QSAR
maximum 50k data
Found 403 Enz. Inhib. hit(s) with all data for entry = 10941
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202656(CHEMBL3916438 | US10730889, Example 419 | US114857...)
Affinity DataIC50:  1.49nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202721(CHEMBL3968268 | US10730889, Example 399 | US114857...)
Affinity DataIC50:  3.31nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202644(CHEMBL3949594 | US10730889, Example 366 | US114857...)
Affinity DataIC50:  3.40nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202664(CHEMBL3925878 | US10730889, Example 408 | US114857...)
Affinity DataIC50:  3.76nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50:  4.32nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455760(BDBM50202668 | N-[[6-(2,4-dimethyloxazole-5- carbo...)
Affinity DataIC50:  4.41nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202646(CHEMBL3889487 | US11485745, Example 290)
Affinity DataIC50:  4.54nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455612(US10730889, Example 200 | US11485745, Example 200 ...)
Affinity DataIC50:  4.56nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455449(N-[[6-(2-phenylacetyl)-6- azaspiro[2.5]octan-2-yl]...)
Affinity DataIC50:  4.59nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455813(N-[[(2S)-6-(3-methylbutanoyl)- 6-azaspiro[2.5]octa...)
Affinity DataIC50:  5.30nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202665(CHEMBL3984355 | US10730889, Example 418 | US114857...)
Affinity DataIC50:  5.60nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580463(N-[[6-[2-(1,4-dimethyl-4- piperidyl)acetyl]-6- aza...)
Affinity DataIC50:  6nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202636(CHEMBL3963163 | US10730889, Example 45 | US1148574...)
Affinity DataIC50:  6.23nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50:  6.36nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580507(N-[[6-[4-(1-methyl-4- piperidyl)benzoyl]-6- azaspi...)
Affinity DataIC50:  6.37nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50:  6.80nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202712(CHEMBL3902837 | US10730889, Example 2 | US11485745...)
Affinity DataIC50:  7.19nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455779((3-methyltetrahydrofuran-3-yl) 2-[(1,3-dihydropyrr...)
Affinity DataIC50:  8.88nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580119(US11485745, Example 3 | tert-butyl 2- [(imidazo[1,...)
Affinity DataIC50:  8.96nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202663(CHEMBL3921880 | US10730889, Example 44 | US1148574...)
Affinity DataIC50:  9.53nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580469(N-[[6-[4-(4-methylpiperazin-1- yl)benzoyl]-6- azas...)
Affinity DataIC50:  9.69nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202644(CHEMBL3949594 | US10730889, Example 366 | US114857...)
Affinity DataIC50:  9.93nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202658(CHEMBL3893879 | US10730889, Example 49 | US1148574...)
Affinity DataIC50:  9.96nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202716(CHEMBL3913883 | US11485745, Example 218)
Affinity DataIC50:  9.97nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455696(N-[[6-(2-phenoxyacetyl)-6- azaspiro[2.5]octan-2-yl...)
Affinity DataIC50:  9.99nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202663(CHEMBL3921880 | US10730889, Example 44 | US1148574...)
Affinity DataIC50:  10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580454(N-[[6-[4-[(4-methylpiperazin-1- yl)methyl]benzoyl]...)
Affinity DataIC50:  10.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580505(N-[[6-[2-[4-methyl-1-(2,2,2- trifluoroethyl)-4- pi...)
Affinity DataIC50:  11nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455430(N-[[6-(3,3-dimethylbutanoyl)-6- azaspiro[2.5]octan...)
Affinity DataIC50:  11.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580308(N-[[6-(3-cyclohexylpropanoyl)- 6-azaspiro[2.5]octa...)
Affinity DataIC50:  11.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202714(CHEMBL3974268 | US10730889, Example 347 | US114857...)
Affinity DataIC50:  11.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202653(CHEMBL3913503 | US10730889, Example 409 | US114857...)
Affinity DataIC50:  11.9nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580313(N-[[6-[2-[3- (trifluoromethyl)phenyl]acetyl]- 6-az...)
Affinity DataIC50:  12nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455760(BDBM50202668 | N-[[6-(2,4-dimethyloxazole-5- carbo...)
Affinity DataIC50:  12.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455799(N-[[6-[4- (trifluoromethyl]pyridine-3- carbonyl]-6...)
Affinity DataIC50:  12.5nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455815(N-[[6-(4-methyloxazole-5- carbonyl)-6-azaspiro[2.5...)
Affinity DataIC50:  12.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202664(CHEMBL3925878 | US10730889, Example 408 | US114857...)
Affinity DataIC50:  12.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455808(N-[[6-(2-pyrimidin-5-ylacetyl)- 6-azaspiro[2.5]oct...)
Affinity DataIC50:  13.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202638(CHEMBL3923552 | US10730889, Example 404 | US114857...)
Affinity DataIC50:  13.6nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455746(N-[[6-[4-(4-Methylpiperazin-1-yl)benzoyl]-6-azaspi...)
Affinity DataIC50:  13.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202641(CHEMBL3930818 | US10730889, Example 42 | US1148574...)
Affinity DataIC50:  14.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580307(N-[[6-(2-cyclohexylacetyl)-6- azaspiro[2.5]octan-2...)
Affinity DataIC50:  14.4nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580310(N-[[6-(3-phenylpropanoyl)-6- azaspiro[2.5]octan-2-...)
Affinity DataIC50:  14.4nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580404(N-[[6-(1-benzyl-3,5-dimethyl- pyrazole-4-carbonyl)...)
Affinity DataIC50:  14.5nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202669(CHEMBL3939767 | US10730889, Example 151 | US114857...)
Affinity DataIC50:  14.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455792(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50:  14.9nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50202670(CHEMBL3904503 | US10730889, Example 219 | US114857...)
Affinity DataIC50:  15.1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455776(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50:  15.2nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580389(N-[[6-[4-(2-methyltetrazol-5- yl)benzoyl]-6- azasp...)
Affinity DataIC50:  15.2nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM580488(US11485745, Example 383 | tert-butyl 2-[(pyrazolo[...)
Affinity DataIC50:  15.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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