Compile Data Set for Download or QSAR
Report error Found 138 Enz. Inhib. hit(s) with all data for entry = 11086
TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589176BDBM589176(US11548903, Example 109)
Affinity DataIC50: 0.149nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589190BDBM589190(US11548903, Example 120)
Affinity DataIC50: 0.186nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589169BDBM589169(US11548903, Example 102)
Affinity DataIC50: 0.241nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589185BDBM589185(US11548903, Example 117)
Affinity DataIC50: 0.287nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589179BDBM589179(US11548903, Example 111)
Affinity DataIC50: 0.320nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589202BDBM589202(US11548903, Example 130)
Affinity DataIC50: 0.405nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589183BDBM589183(US11548903, Example 115)
Affinity DataIC50: 1.01nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589168BDBM589168(US11548903, Example 101)
Affinity DataIC50: 1.03nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589206BDBM589206(US11548903, Example 134)
Affinity DataIC50: 1.40nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589178BDBM589178(US11548903, Example 110)
Affinity DataIC50: 1.56nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589192BDBM589192(US11548903, Example 121)
Affinity DataIC50: 1.59nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589202BDBM589202(US11548903, Example 130)
Affinity DataIC50: 1.78nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589168BDBM589168(US11548903, Example 101)
Affinity DataIC50: 1.84nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589170BDBM589170(US11548903, Example 103)
Affinity DataIC50: 1.86nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589193BDBM589193(US11548903, Example 122)
Affinity DataIC50: 2.36nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589184BDBM589184(US11548903, Example 116)
Affinity DataIC50: 2.53nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589195BDBM589195(US11548903, Example 124)
Affinity DataIC50: 2.62nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589175BDBM589175(US11548903, Example 108)
Affinity DataIC50: 2.71nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589185BDBM589185(US11548903, Example 117)
Affinity DataIC50: 2.79nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589169BDBM589169(US11548903, Example 102)
Affinity DataIC50: 3.08nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589203BDBM589203(US11548903, Example 131)
Affinity DataIC50: 3.83nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589207BDBM589207(US11548903, Example 135)
Affinity DataIC50: 4.30nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589206BDBM589206(US11548903, Example 134)
Affinity DataIC50: 4.30nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589194BDBM589194(US11548903, Example 123)
Affinity DataIC50: 4.5nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589179BDBM589179(US11548903, Example 111)
Affinity DataIC50: 5.18nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589176BDBM589176(US11548903, Example 109)
Affinity DataIC50: 5.49nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589187BDBM589187(US11548903, Example 118)
Affinity DataIC50: 7.45nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589212BDBM589212(US11548903, Example 140)
Affinity DataIC50: 8.70nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589182BDBM589182(US11548903, Example 114)
Affinity DataIC50: 8.96nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589188BDBM589188(US11548903, Example 119)
Affinity DataIC50: 9.45nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589174BDBM589174(US11548903, Example 107)
Affinity DataIC50: 11.7nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589209BDBM589209(US11548903, Example 137)
Affinity DataIC50: 15nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589183BDBM589183(US11548903, Example 115)
Affinity DataIC50: 15.3nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589200BDBM589200(US11548903, Example 128)
Affinity DataIC50: 15.3nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589211BDBM589211(US11548903, Example 139)
Affinity DataIC50: 15.8nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589197BDBM589197(US11548903, Example 126)
Affinity DataIC50: 20.1nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589216BDBM589216(US11548903, Example 144)
Affinity DataIC50: 21.6nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589207BDBM589207(US11548903, Example 135)
Affinity DataIC50: 22.3nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589181BDBM589181(US11548903, Example 113)
Affinity DataIC50: 22.6nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589170BDBM589170(US11548903, Example 103)
Affinity DataIC50: 27.2nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589210BDBM589210(US11548903, Example 138)
Affinity DataIC50: 27.2nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589182BDBM589182(US11548903, Example 114)
Affinity DataIC50: 30.6nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589190BDBM589190(US11548903, Example 120)
Affinity DataIC50: 34nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589175BDBM589175(US11548903, Example 108)
Affinity DataIC50: 34nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589214BDBM589214(US11548903, Example 142)
Affinity DataIC50: 37.2nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589181BDBM589181(US11548903, Example 113)
Affinity DataIC50: 38.1nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589217BDBM589217(US11548903, Example 145)
Affinity DataIC50: 48.5nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589184BDBM589184(US11548903, Example 116)
Affinity DataIC50: 52nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589172BDBM589172(US11548903, Example 105)
Affinity DataIC50: 56.9nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 589172BDBM589172(US11548903, Example 105)
Affinity DataIC50: 64.4nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

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