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Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 11294
TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259423(US10457647, Example 22 | US11180460, Example 22 | ...)
Affinity DataIC50: <0.100nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259427(US10457647, Example 26 | US11180460, Example 26 | ...)
Affinity DataIC50:  0.400nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259425(US10457647, Example 24 | US11180460, Example 24 | ...)
Affinity DataIC50:  0.5nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259404(US10457647, Example 3 | US11180460, Example 3 | US...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259440(US10457647, Example 39 | US11180460, Example 39 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259426(US10457647, Example 25 | US11180460, Example 25 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259424(US10457647, Example 23 | US11180460, Example 23 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259429(US10457647, Example 28 | US11180460, Example 28 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259419(US10457647, Example 18 | US11180460, Example 18 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259416(US10457647, Example 15 | US11180460, Example 15 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259415(US10457647, Example 14 | US11180460, Example 14 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259434(US10457647, Example 33 | US11180460, Example 33 | ...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259407(US10457647, Example 6 | US11180460, Example 6 | US...)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259441(US10457647, Example 40 | US11180460, Example 40 | ...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259422(US10457647, Example 21 | US11180460, Example 21 | ...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259439(US10457647, Example 38 | US11180460, Example 38 | ...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259402(US10457647, Example 1 | US11180460, Example 1 | US...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259432(US10457647, Example 31 | US11180460, Example 31 | ...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259436(US10457647, Example 35 | US11180460, Example 35 | ...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259409(US10457647, Example 8 | US11180460, Example 8 | US...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259435(US10457647, Example 34 | US11180460, Example 34 | ...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259428(US10457647, Example 27 | US11180460, Example 27 | ...)
Affinity DataIC50:  3nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259406(US10457647, Example 5 | US11180460, Example 5 | US...)
Affinity DataIC50:  4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259433(US10457647, Example 32 | US11180460, Example 32 | ...)
Affinity DataIC50:  4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259430(US10457647, Example 29 | US11180460, Example 29 | ...)
Affinity DataIC50:  4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259411(US10457647, Example 10 | US11180460, Example 10 | ...)
Affinity DataIC50:  4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259418(US10457647, Example 17 | US11180460, Example 17 | ...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259421(US10457647, Example 20 | US11180460, Example 20 | ...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259431(US10457647, Example 30 | US11180460, Example 30 | ...)
Affinity DataIC50:  6nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259414(US10457647, Example 13 | US11180460, Example 13 | ...)
Affinity DataIC50:  7nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259405(US10457647, Example 4 | US11180460, Example 4 | US...)
Affinity DataIC50:  9nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259410(US10457647, Example 9 | US11180460, Example 9 | US...)
Affinity DataIC50:  10nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259412(US10457647, Example 11 | US11180460, Example 11 | ...)
Affinity DataIC50:  10nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259413(US10457647, Example 12 | US11180460, Example 12 | ...)
Affinity DataIC50:  12nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259417(US10457647, Example 16 | US11180460, Example 16 | ...)
Affinity DataIC50:  15nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259420(US10457647, Example 19 | US11180460, Example 19 | ...)
Affinity DataIC50:  16nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259437(US10457647, Example 36 | US11180460, Example 36 | ...)
Affinity DataIC50:  17nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259438(US10457647, Example 37 | US11180460, Example 37 | ...)
Affinity DataIC50:  32nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259403(US10457647, Example 2 | US11180460, Example 2 | US...)
Affinity DataIC50:  38nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259408(US10457647, Example 7 | US11180460, Example 7 | US...)
Affinity DataIC50:  42nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent