Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 12045
TargetMelatonin receptor type 1A(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674468(N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)ace...)
Affinity DataIC50: 0.230nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetMelatonin receptor type 1A(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674467(N-(2-(6-chloro-7-deuteromethoxy-naphthalen-1-yl)et...)
Affinity DataIC50: 0.450nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetMelatonin receptor type 1B(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674468(N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)ace...)
Affinity DataIC50: 0.670nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetMelatonin receptor type 1A(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataIC50: 0.690nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMelatonin receptor type 1B(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674467(N-(2-(6-chloro-7-deuteromethoxy-naphthalen-1-yl)et...)
Affinity DataIC50: 0.720nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674467(N-(2-(6-chloro-7-deuteromethoxy-naphthalen-1-yl)et...)
Affinity DataIC50: 0.770nMAssay Description:The test tubes were placed under a reaction condition of 25° C. 50 μg of the receptor membrane protein 5-HT2C was added to all the tubes. In non...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetMelatonin receptor type 1B(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataIC50: 0.990nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataIC50: 4.52nMAssay Description:The test tubes were placed under a reaction condition of 25° C. 50 μg of the receptor membrane protein 5-HT2C was added to all the tubes. In non...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674468(N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)ace...)
Affinity DataIC50: 20.8nMAssay Description:The test tubes were placed under a reaction condition of 25° C. 50 μg of the receptor membrane protein 5-HT2C was added to all the tubes. In non...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent