Compile Data Set for Download or QSAR
Report error Found 279 Enz. Inhib. hit(s) with all data for entry = 13045
LigandChemical structure of BindingDB Monomer ID 50547871BDBM50547871(CHEMBL4757194 | US12344603, Compound 123)
Affinity DataIC50: 0.0500nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50547872BDBM50547872(CHEMBL4777304 | US12344603, Compound 129)
Affinity DataIC50: 0.0800nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50547873BDBM50547873(CHEMBL4789787 | US12344603, Compound 166)
Affinity DataIC50: 0.0900nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754995BDBM754995(1-(2,2-difluorocyclo- pentyl)-N-[4-[2-[[4- (dimeth...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754978BDBM754978(N-[4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754962BDBM754962(2-cyclobutyl-N-(4-(2- (((1r,4r)-4-(dimethyl- amino...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754994BDBM754994(1-(2,2-difluorocyclo- butyl)-N-[4-[2-[[4- (dimethy...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754897BDBM754897(N-4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)am...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754976BDBM754976(N-[4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50547870BDBM50547870(CHEMBL4798215 | US12344603, Compound 81)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754973BDBM754973(N-[4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50547874BDBM50547874(CHEMBL4748828 | US12344603, Compound 240)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754999BDBM754999(N-(4-[2-[[4-(dimethyl- amino)cyclohexyl]- amino]-8...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754998BDBM754998(1-cyclopentyl-N-[4-[2- [[4-(dimethylamino)- cycloh...)
Affinity DataIC50: 0.100nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754861BDBM754861(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.110nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754765BDBM754765(1-(3-methoxyphenyl)- N-(2,3,6-trifluoro-4-(2- (((3...)
Affinity DataIC50: 0.110nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754924BDBM754924(N-(4-(2-((4-(dimethyl- amino)-3-fluorocyclo- hexyl...)
Affinity DataIC50: 0.110nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754915BDBM754915(N-(2-fluoro-4-(2- (((1r,4r)-4-((2-fluoro- ethyl)(m...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754858BDBM754858(N-(2-fluoro-4-(8-iso- propyl-2-(((1r,4r)-4- ((2-me...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754856BDBM754856(N-(2,6-difluoro-4-(8- isopropyl-2-(((1r,4r)- 4-((2...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754855BDBM754855(N-(5-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754903BDBM754903(1-(4-fluorophenyl)-N- (2,3,6-trifluoro-4-(2- (((3S...)
Affinity DataIC50: 0.120nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754802BDBM754802(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754846BDBM754846(N-(2-fluoro-4-(2- (((3S,5S)-5-fluoropiper- idin-3-...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754845BDBM754845(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754843BDBM754843(1-cyclopentyl-N-(4-(2- (((1r,4r)-4-(dimethyl- amin...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754825BDBM754825(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754841BDBM754841(1-(2-cyano-4-methyl- phenyl)-N-(2,3,6- trifluoro-4...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754888BDBM754888((N-(4-(2-((4-(dimethyl- amino)-3-fluorocyclo- hexy...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754902BDBM754902(1-p-tolyl-N-(2,3,6- trifluoro-4-(2-(((3S,5S)- 5-fl...)
Affinity DataIC50: 0.130nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754944BDBM754944(3,3,3-Trifluoro-N-(2- fluoro-4-(8-isopropyl- 2-(((...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754908BDBM754908(N-(2-(fluoro-4-(2- (((1r,4r)-4-((2-fluoro- ethyl)(...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754891BDBM754891(3,3,3-trifluoro-N-(2- fluoro-4-(2-(((1r,4r)-4- ((2...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754907BDBM754907(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754936BDBM754936(N-(4-(2-(((1,4-trans)-4- (ethyl(methyl)amino)- cyc...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754791BDBM754791(1-(4-methoxyphenyl)- N-(2,3,6-trifluoro-4-(2- (((3...)
Affinity DataIC50: 0.140nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754849BDBM754849(1-cyclohexyl-N-(4-(2- (((1r,4r)-4-(dimethyl- amino...)
Affinity DataIC50: 0.150nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754862BDBM754862(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.150nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754840BDBM754840(N-(5-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.150nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754853BDBM754853(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754820BDBM754820(1-(2-fluorophenyl)-N- (2,3,6-trifluoro-4-(2- (((3S...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754836BDBM754836(1-phenyl-N-(2,3,6- trifluoro-4-(8-isopropyl- 2-((4...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754913BDBM754913(N-(4-(2-((4-(dimethyl- amino)-3-fluorocyclo- hexyl...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754880BDBM754880(2-chloro-N-(5-(2- (((1r,4r)-4-((2-fluoro- ethyl)(m...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754839BDBM754839(2-chloro-N-(5-(2- (((1r,4r)-4-(dimethyl- amino)cyc...)
Affinity DataIC50: 0.160nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754917BDBM754917(1-phenyl-N-(2,3,6- trifluoro-4-(2-(((3S,5S)- 5-flu...)
Affinity DataIC50: 0.170nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754937BDBM754937(3,3,3-trifluoro-N-(2- fluoro-4-(8-isopropyl-2- (((...)
Affinity DataIC50: 0.170nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754790BDBM754790(N-(4-(2-(((1r,4r)-4- aminocyclohexyl)- amino)-8-is...)
Affinity DataIC50: 0.170nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754851BDBM754851(N-(4-(2-(((1r,4r)-4- (dimethylamino)cyclo- hexyl)a...)
Affinity DataIC50: 0.180nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 754899BDBM754899(2-chloro-N-(4-(2- (((1r,4r)-4-(dimethyl- amino)cyc...)
Affinity DataIC50: 0.180nMAssay Description:A His-tagged IRE1α kinase dead construct containing the kinase and RNase domains (KR, AA G547-L977, D688N) was expressed in Sf9 insect cells. The pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

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