Compile Data Set for Download or QSAR
Report error Found 364 Enz. Inhib. hit(s) with all data for entry = 13283
TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773873BDBM773873(US12427146, Compound 108)
Affinity DataIC50: 2.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773904BDBM773904(US12427146, Compound 139)
Affinity DataIC50: 2.70nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773883BDBM773883(US12427146, Compound 118)
Affinity DataIC50: 2.80nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773797BDBM773797(US12427146, Compound 32)
Affinity DataIC50: 2.90nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773908BDBM773908(US12427146, Compound 143)
Affinity DataIC50: 3.60nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773884BDBM773884(US12427146, Compound 119)
Affinity DataIC50: 3.70nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773788BDBM773788(US12427146, Compound 23)
Affinity DataIC50: 4.10nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773951BDBM773951(US12427146, Compound 186)
Affinity DataIC50: 4.10nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773914BDBM773914(US12427146, Compound 149)
Affinity DataIC50: 4.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773874BDBM773874(US12427146, Compound 109)
Affinity DataIC50: 4.60nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773916BDBM773916(US12427146, Compound 151)
Affinity DataIC50: 4.80nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773950BDBM773950(US12427146, Compound 185)
Affinity DataIC50: 4.90nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773949BDBM773949(US12427146, Compound 184)
Affinity DataIC50: 5.20nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773937BDBM773937(US12427146, Compound 172)
Affinity DataIC50: 5.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773936BDBM773936(US12427146, Compound 171)
Affinity DataIC50: 5.60nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773892BDBM773892(US12427146, Compound 127)
Affinity DataIC50: 5.80nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773917BDBM773917(US12427146, Compound 152)
Affinity DataIC50: 6nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773845BDBM773845(US12427146, Compound 80)
Affinity DataIC50: 6nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773944BDBM773944(US12427146, Compound 179)
Affinity DataIC50: 6.20nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773927BDBM773927(US12427146, Compound 162)
Affinity DataIC50: 6.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773940BDBM773940(US12427146, Compound 175)
Affinity DataIC50: 6.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773906BDBM773906(US12427146, Compound 141)
Affinity DataIC50: 6.80nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773913BDBM773913(US12427146, Compound 148)
Affinity DataIC50: 6.90nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773880BDBM773880(US12427146, Compound 115)
Affinity DataIC50: 7.10nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773952BDBM773952(US12427146, Compound 187)
Affinity DataIC50: 7.30nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773918BDBM773918(US12427146, Compound 153)
Affinity DataIC50: 7.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773928BDBM773928(US12427146, Compound 163)
Affinity DataIC50: 7.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773894BDBM773894(US12427146, Compound 129)
Affinity DataIC50: 7.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773943BDBM773943(US12427146, Compound 178)
Affinity DataIC50: 7.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773844BDBM773844(US12427146, Compound 79)
Affinity DataIC50: 7.60nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773946BDBM773946(US12427146, Compound 181)
Affinity DataIC50: 7.80nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773915BDBM773915(US12427146, Compound 150)
Affinity DataIC50: 8.10nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773947BDBM773947(US12427146, Compound 182)
Affinity DataIC50: 8.30nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773903BDBM773903(US12427146, Compound 138)
Affinity DataIC50: 8.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773839BDBM773839(US12427146, Compound 74)
Affinity DataIC50: 8.80nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773934BDBM773934(US12427146, Compound 169)
Affinity DataIC50: 9.10nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773921BDBM773921(US12427146, Compound 156)
Affinity DataIC50: 9.30nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773827BDBM773827(US12427146, Compound 62)
Affinity DataIC50: 9.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773930BDBM773930(US12427146, Compound 165)
Affinity DataIC50: 9.90nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773926BDBM773926(US12427146, Compound 161)
Affinity DataIC50: 10.1nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773941BDBM773941(US12427146, Compound 176)
Affinity DataIC50: 10.2nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773938BDBM773938(US12427146, Compound 173)
Affinity DataIC50: 10.3nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773907BDBM773907(US12427146, Compound 142)
Affinity DataIC50: 10.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773948BDBM773948(US12427146, Compound 183)
Affinity DataIC50: 11.2nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773953BDBM773953(US12427146, Compound 188)
Affinity DataIC50: 11.4nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773843BDBM773843(US12427146, Compound 78)
Affinity DataIC50: 11.8nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773893BDBM773893(US12427146, Compound 128)
Affinity DataIC50: 12nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773919BDBM773919(US12427146, Compound 154)
Affinity DataIC50: 12.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773826BDBM773826(US12427146, Compound 61)
Affinity DataIC50: 12.6nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 773933BDBM773933(US12427146, Compound 168)
Affinity DataIC50: 12.7nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

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