Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 13493
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataIC50: 2.20nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 2.20nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataKi:  6.90nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 7.10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 9.60nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataKi:  864nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataIC50: 2.50E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataIC50: 2.70E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent