Compile Data Set for Download or QSAR
Report error Found 200 Enz. Inhib. hit(s) with all data for entry = 11589
TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629510BDBM629510(US20230339981, Example 198)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629513BDBM629513(US20230339981, Example 201)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629509BDBM629509(US20230339981, Example 197)
Affinity DataIC50: 0.0400nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629518BDBM629518(US20230339981, Example 206)
Affinity DataIC50: 0.0400nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629381BDBM629381(US20230339981, Example 68)
Affinity DataIC50: 0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629505BDBM629505(US20230339981, Example 193)
Affinity DataIC50: 0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629512BDBM629512(US20230339981, Example 200)
Affinity DataIC50: 0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629519BDBM629519(US20230339981, Example 207)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629387BDBM629387(US20230339981, Example 75)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629517BDBM629517(US20230339981, Example 205)
Affinity DataIC50: 0.0600nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629507BDBM629507(US20230339981, Example 195)
Affinity DataIC50: 0.0700nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629511BDBM629511(US20230339981, Example 199)
Affinity DataIC50: 0.0700nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629380BDBM629380(US20230339981, Example 67)
Affinity DataIC50: 0.0800nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629520BDBM629520(US20230339981, Example 208)
Affinity DataIC50: 0.0900nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629475BDBM629475(US20230339981, Example 163)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629477BDBM629477(US20230339981, Example 165)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629483BDBM629483(US20230339981, Example 171)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629421BDBM629421(US20230339981, Example 109)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629485BDBM629485(US20230339981, Example 173)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629479BDBM629479(US20230339981, Example 167)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629422BDBM629422(US20230339981, Example 110 | US20230339981, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629460BDBM629460(US20230339981, Example 148)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629461BDBM629461(US20230339981, Example 149)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629392BDBM629392(US20230339981, Example 80 | US20230339981, Example...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629467BDBM629467(US20230339981, Example 155)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629340BDBM629340(US20230339981, Example 22)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629406BDBM629406(US20230339981, Example 94)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629463BDBM629463(US20230339981, Example 151 | US20230339981, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629464BDBM629464(US20230339981, Example 152)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629466BDBM629466(US20230339981, Example 154)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629508BDBM629508(US20230339981, Example 196)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629445BDBM629445(US20230339981, Example 133)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629382BDBM629382(US20230339981, Example 69)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629504BDBM629504(US20230339981, Example 192)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629377BDBM629377(US20230339981, Example 64)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629451BDBM629451(US20230339981, Example 139)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629388BDBM629388(US20230339981, Example 76)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629516BDBM629516(US20230339981, Example 204)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629383BDBM629383(US20230339981, Example 70)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629427BDBM629427(US20230339981, Example 115)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629491BDBM629491(US20230339981, Example 179)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629429BDBM629429(US20230339981, Example 117)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629488BDBM629488(US20230339981, Example 176)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629489BDBM629489(US20230339981, Example 177)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629435BDBM629435(US20230339981, Example 123)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629501BDBM629501(US20230339981, Example 189)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629502BDBM629502(US20230339981, Example 190)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629368BDBM629368(US20230339981, Example 52)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629369BDBM629369(US20240025919, Compound 7 | US20230339981, Example...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 629434BDBM629434(US20230339981, Example 122)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

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