Compile Data Set for Download or QSAR
Report error Found 373 Enz. Inhib. hit(s) with all data for entry = 11786
TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647873BDBM647873(US20240025919, Compound 104)
Affinity DataIC50: 0.0500nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647782BDBM647782(US20240025919, Compound 9)
Affinity DataIC50: 0.0570nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647776BDBM647776(US20240025919, Compound 3 | US20240327425, Compoun...)
Affinity DataIC50: 0.0580nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 629369BDBM629369(US20240025919, Compound 7 | US20230339981, Example...)
Affinity DataIC50: 0.0590nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647778BDBM647778(US20240025919, Compound 5 | US20240327434, Compoun...)
Affinity DataIC50: 0.0600nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647784BDBM647784(US20240025919, Compound 11)
Affinity DataIC50: 0.0600nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647850BDBM647850(US20240025919, Compound 80)
Affinity DataIC50: 0.0680nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647788BDBM647788(US20240025919, Compound 15)
Affinity DataIC50: 0.0700nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647838BDBM647838(US20240025919, Compound 68)
Affinity DataIC50: 0.0700nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 648017BDBM648017(US20240025919, Compound 258)
Affinity DataIC50: 0.0700nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647779BDBM647779(US20240025919, Compound 6)
Affinity DataIC50: 0.0740nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647901BDBM647901(US20240025919, Compound 133)
Affinity DataIC50: 0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647901BDBM647901(US20240025919, Compound 133)
Affinity DataIC50: 0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647930BDBM647930(US20240025919, Compound 165)
Affinity DataIC50: 0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647938BDBM647938(US20240025919, Compound 173)
Affinity DataIC50: 0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647792BDBM647792(US20240025919, Compound 19)
Affinity DataIC50: 0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647901BDBM647901(US20240025919, Compound 133)
Affinity DataIC50: 0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647783BDBM647783(US20240025919, Compound 10)
Affinity DataIC50: 0.0820nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647832BDBM647832(US20240025919, Compound 62)
Affinity DataIC50: 0.0830nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 629322BDBM629322(US20240025919, Compound 81 | US20230339981, Exampl...)
Affinity DataIC50: 0.0850nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647802BDBM647802(US20240025919, Compound 29)
Affinity DataIC50: 0.0860nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647804BDBM647804(US20240025919, Compound 31)
Affinity DataIC50: 0.0870nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 648017BDBM648017(US20240025919, Compound 258)
Affinity DataIC50: 0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647930BDBM647930(US20240025919, Compound 165)
Affinity DataIC50: 0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647930BDBM647930(US20240025919, Compound 165)
Affinity DataIC50: 0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647886BDBM647886(US20240025919, Compound 118)
Affinity DataIC50: 0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647935BDBM647935(US20240025919, Compound 170)
Affinity DataIC50: 0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647931BDBM647931(US20240025919, Compound 166)
Affinity DataIC50: 0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647894BDBM647894(US20240025919, Compound 126)
Affinity DataIC50: 0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647963BDBM647963(US20240025919, Compound 200)
Affinity DataIC50: 0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647918BDBM647918(US20240025919, Compound 153 | US20240025919, Compo...)
Affinity DataIC50: 0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647934BDBM647934(US20240025919, Compound 169)
Affinity DataIC50: 0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647950BDBM647950(US20240025919, Compound 186)
Affinity DataIC50: 0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647890BDBM647890(US20240025919, Compound 122)
Affinity DataIC50: 0.110nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647954BDBM647954(US20240025919, Compound 190)
Affinity DataIC50: 0.110nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647928BDBM647928(US20240025919, Compound 163)
Affinity DataIC50: 0.110nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647834BDBM647834(US20240025919, Compound 64)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647901BDBM647901(US20240025919, Compound 133)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647793BDBM647793(US20240025919, Compound 20)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647925BDBM647925(US20240025919, Compound 160)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647917BDBM647917(US20240025919, Compound 151)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647933BDBM647933(US20240025919, Compound 168)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 629325BDBM629325(Compound 5 (5-fluoro-4-((5aS,6S,9R)-1-fluoro-12-((...)
Affinity DataIC50: 0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 648000BDBM648000(US20240025919, Compound 241)
Affinity DataIC50: 0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647846BDBM647846(US20240025919, Compound 76)
Affinity DataIC50: 0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647927BDBM647927(US20240025919, Compound 162)
Affinity DataIC50: 0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647845BDBM647845(US20240025919, Compound 75)
Affinity DataIC50: 0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647790BDBM647790(US20240025919, Compound 17)
Affinity DataIC50: 0.133nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647789BDBM647789(US20240025919, Compound 16)
Affinity DataIC50: 0.138nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 647908BDBM647908(US20240025919, Compound 140)
Affinity DataIC50: 0.140nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

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