Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 12305
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694446(US20240293400, Compound 2)
Affinity DataIC50: 2.33nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694446(US20240293400, Compound 2)
Affinity DataIC50: 2.36nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694445(US20240293400, Compound 1)
Affinity DataIC50: 2.5nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694445(US20240293400, Compound 1)
Affinity DataIC50: 5.36nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694447(US20240293400, Compound 3)
Affinity DataIC50: 6.30nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694447(US20240293400, Compound 3)
Affinity DataIC50: 48.2nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent