Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12913
TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739808BDBM739808(US20250154131, Compound 9)
Affinity DataIC50: 25.2nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739807BDBM739807(US20250154131, Compound 8)
Affinity DataIC50: 33.4nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739798BDBM739798(US20250154131, Compound 1-P2)
Affinity DataIC50: 35.3nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739810BDBM739810(US20250154131, Compound 10)
Affinity DataIC50: 69.8nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739804BDBM739804((1R,2S,5S)—N-((1S)-1-Cyano-2-(2-carbonylindolin-3-...)
Affinity DataIC50: 69.8nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739800BDBM739800(US20250154131, Compound 2)
Affinity DataIC50: 74.1nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739802BDBM739802((1R,2S,5S)—N—((S)-1-Cyano-2-((S)-2-carbonylpyrroli...)
Affinity DataIC50: 273nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739805BDBM739805(US20250154131, Compound 6)
Affinity DataIC50: 449nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739801BDBM739801(US20250154131, Compound 3)
Affinity DataIC50: 525nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 739806BDBM739806(US20250154131, Compound 7)
Affinity DataIC50: 1.11E+3nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent