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Found 65 Enz. Inhib. hit(s) with all data for entry = 6299
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120985(US8716285, 42)
Affinity DataIC50:  160nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120989(US8716285, 46)
Affinity DataIC50:  190nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120987(US8716285, 44)
Affinity DataIC50:  210nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120955(US8716285, 12)
Affinity DataIC50:  260nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120952(US8716285, 9)
Affinity DataIC50:  290nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120958(US8716285, 15)
Affinity DataIC50:  300nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120951(US8716285, 8)
Affinity DataIC50:  300nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120974(US8716285, 31)
Affinity DataIC50:  320nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120983(US8716285, 40)
Affinity DataIC50:  350nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120991(US8716285, 48)
Affinity DataIC50:  370nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120986(US8716285, 43)
Affinity DataIC50:  370nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120988(US8716285, 45)
Affinity DataIC50:  390nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120996(US8716285, 53)
Affinity DataIC50:  470nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120990(US8716285, 47)
Affinity DataIC50:  470nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120968(US8716285, 25)
Affinity DataIC50:  480nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120977(US8716285, 34)
Affinity DataIC50:  480nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120973(US8716285, 30)
Affinity DataIC50:  510nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120970(US8716285, 27)
Affinity DataIC50:  520nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120969(US8716285, 26)
Affinity DataIC50:  520nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120945(US8716285, 2)
Affinity DataIC50:  680nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120967(US8716285, 24)
Affinity DataIC50:  720nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120950(US8716285, 7)
Affinity DataIC50:  730nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121008(US8716285, 65)
Affinity DataIC50:  750nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120954(US8716285, 11)
Affinity DataIC50:  800nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120959(US8716285, 16)
Affinity DataIC50:  800nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121009(US8716285, 66)
Affinity DataIC50:  830nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120984(US8716285, 41)
Affinity DataIC50:  850nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120972(US8716285, 29)
Affinity DataIC50:  900nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120982(US8716285, 39)
Affinity DataIC50:  910nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120949(US8716285, 6)
Affinity DataIC50:  930nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120995(US8716285, 52)
Affinity DataIC50:  930nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121004(US8716285, 61)
Affinity DataIC50:  970nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120980(US8716285, 37)
Affinity DataIC50:  990nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120971(US8716285, 28)
Affinity DataIC50:  1.00E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120960(US8716285, 17)
Affinity DataIC50:  1.10E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121005(US8716285, 62)
Affinity DataIC50:  1.14E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121007(US8716285, 64)
Affinity DataIC50:  1.22E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120961(US8716285, 18)
Affinity DataIC50:  1.23E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120981(US8716285, 38)
Affinity DataIC50:  1.27E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120994(US8716285, 51)
Affinity DataIC50:  1.28E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120966(US8716285, 23)
Affinity DataIC50:  1.44E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121003(US8716285, 60)
Affinity DataIC50:  1.46E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120975(US8716285, 32)
Affinity DataIC50:  1.50E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120993(US8716285, 50)
Affinity DataIC50:  1.51E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120963(US8716285, 20)
Affinity DataIC50:  1.52E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121006(US8716285, 63)
Affinity DataIC50:  1.61E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120957(US8716285, 14)
Affinity DataIC50:  1.66E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120962(US8716285, 19)
Affinity DataIC50:  1.69E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120978(US8716285, 35)
Affinity DataIC50:  1.78E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120953(US8716285, 10)
Affinity DataIC50:  2.13E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
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