Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 6381
TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125218BDBM125218(US8772481, 16)
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125219BDBM125219(US8772481, 5)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125210BDBM125210(US8772481, 10)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125207BDBM125207(US8772481, 7)
Affinity DataIC50: 0.5nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125206BDBM125206(US8772481, 6)
Affinity DataIC50: 0.5nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125220BDBM125220(US8772481, 17)
Affinity DataIC50: 0.700nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125222BDBM125222(US8772481, 19)
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125209BDBM125209(US8772481, 9)
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125215BDBM125215(US8772481, 14)
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125208BDBM125208(US8772481, 8)
Affinity DataIC50: 1.20nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125223BDBM125223(US8772481, 20)
Affinity DataIC50: 1.20nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125214BDBM125214(US8772481, 2)
Affinity DataIC50: 1.60nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125213BDBM125213(US8772481, 13)
Affinity DataIC50: 3.5nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125217BDBM125217(US8772481, 3)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125221BDBM125221(US8772481, 18)
Affinity DataIC50: 5.10nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125212BDBM125212(US8772481, 12)
Affinity DataIC50: 5.60nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125224BDBM125224(US8772481, 21)
Affinity DataIC50: 6.5nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125216BDBM125216(US8772481, 15)
Affinity DataIC50: 7.10nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125211BDBM125211(US8772481, 11)
Affinity DataIC50: 45nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125225BDBM125225(US8772481, 22)
Affinity DataIC50: 168nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125226BDBM125226(US8772481, 23)
Affinity DataIC50: 417nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent