Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with all data for entry = 6546
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138350BDBM138350(US8877944, 100)
Affinity DataKd: <10nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138348BDBM138348(US8877944, 99)
Affinity DataIC50: 10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138349BDBM138349(US8877944, 103)
Affinity DataKd: <10nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138354BDBM138354(US8877944, 105)
Affinity DataKd: <10nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138298BDBM138298(US8877944, 7)
Affinity DataKd: <10nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138348BDBM138348(US8877944, 99)
Affinity DataKd: <10nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138301BDBM138301(US8877944, 3)
Affinity DataKd:  13nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138302BDBM138302(US8877944, 4)
Affinity DataKd:  20nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138300BDBM138300(US8877944, 2)
Affinity DataKd:  25nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138335BDBM138335(US8877944, 39)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138339BDBM138339(US8877944, 43)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138331BDBM138331(US8877944, 35)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138332BDBM138332(US8877944, 36)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138333BDBM138333(US8877944, 37)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138334BDBM138334(US8877944, 38)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138308BDBM138308(US8877944, 12)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138309BDBM138309(US8877944, 13)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138304BDBM138304(US8877944, 6)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138341BDBM138341(US8877944, 45)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138342BDBM138342(US8877944, 47)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138346BDBM138346(US8877944, 51)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138318BDBM138318(US8877944, 22)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138312BDBM138312(US8877944, 16)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138313BDBM138313(US8877944, 17)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138314BDBM138314(US8877944, 18)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138325BDBM138325(US8877944, 29)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138327BDBM138327(US8877944, 31)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138321BDBM138321(US8877944, 25)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138322BDBM138322(US8877944, 26)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138323BDBM138323(US8877944, 27)
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138338BDBM138338(US8877944, 42)
Affinity DataKd:  33nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138324BDBM138324(US8877944, 28)
Affinity DataKd:  34nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138315BDBM138315(US8877944, 19)
Affinity DataKd:  40nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138303BDBM138303(US8877944, 5)
Affinity DataKd:  40nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138344BDBM138344(US8877944, 49)
Affinity DataIC50: 40nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138307BDBM138307(US8877944, 11)
Affinity DataKd:  40nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138328BDBM138328(US8877944, 32)
Affinity DataKd:  40nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138306BDBM138306(US8877944, 10)
Affinity DataKd:  40nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138317BDBM138317(US8877944, 21)
Affinity DataKd:  50nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138319BDBM138319(US8877944, 23)
Affinity DataKd:  50nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138311BDBM138311(US8877944, 15)
Affinity DataKd:  50nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138299BDBM138299(US8877944, 1)
Affinity DataKd:  60nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138310BDBM138310(US8877944, 14)
Affinity DataKd:  66nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138349BDBM138349(US8877944, 103)
Affinity DataIC50: 80nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138354BDBM138354(US8877944, 105)
Affinity DataIC50: 80nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138351BDBM138351(US8877944, 101)
Affinity DataIC50: 1.90E+3nM Kd:  80nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138342BDBM138342(US8877944, 47)
Affinity DataIC50: 80nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138302BDBM138302(US8877944, 4)
Affinity DataIC50: 90nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138325BDBM138325(US8877944, 29)
Affinity DataIC50: 100nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 138336BDBM138336(US8877944, 40)
Affinity DataKd:  110nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

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