Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 6673
TargetCytochrome P450 3A4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 144637BDBM144637(US8952036, Ex. 5)
Affinity DataIC50: 0.0503nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50448963BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
Affinity DataIC50: 0.0962nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 144636BDBM144636(US8952036, Ex. 4)
Affinity DataIC50: 0.102nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 144638BDBM144638(US8952036, Ex. 3)
Affinity DataIC50: 0.330nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50008760BDBM50008760(CHEMBL3236364)
Affinity DataIC50: 1.83nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent