Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 6719
TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149692BDBM149692(US8975267, 34)
Affinity DataIC50: 0.800nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149692BDBM149692(US8975267, 34)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149689BDBM149689(US8975267, 30)
Affinity DataIC50: 4nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149691BDBM149691(US8975267, 33)
Affinity DataIC50: 5nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149691BDBM149691(US8975267, 33)
Affinity DataIC50: 7nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149693BDBM149693(US8975267, 35)
Affinity DataIC50: 7nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149689BDBM149689(US8975267, 30)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149694BDBM149694(US8975267, 36)
Affinity DataIC50: 13nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149686BDBM149686(US8975267, 22)
Affinity DataIC50: 16nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149685BDBM149685(US8975267, 7)
Affinity DataIC50: 23nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149693BDBM149693(US8975267, 35)
Affinity DataIC50: 23nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149695BDBM149695(US8975267, 38)
Affinity DataIC50: 24nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149686BDBM149686(US8975267, 22)
Affinity DataIC50: 24nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149695BDBM149695(US8975267, 38)
Affinity DataIC50: 34nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149694BDBM149694(US8975267, 36)
Affinity DataIC50: 46nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149690BDBM149690(US8975267, 32)
Affinity DataIC50: 74nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149688BDBM149688(US8975267, 29)
Affinity DataIC50: 87nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149684BDBM149684(US8975267, 3)
Affinity DataIC50: 99nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 47183BDBM47183(US8975267, 16)
Affinity DataIC50: 132nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149687BDBM149687(US8975267, 25)
Affinity DataIC50: 133nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149690BDBM149690(US8975267, 32)
Affinity DataIC50: 159nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149686BDBM149686(US8975267, 22)
Affinity DataIC50: 382nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149688BDBM149688(US8975267, 29)
Affinity DataIC50: 408nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149687BDBM149687(US8975267, 25)
Affinity DataIC50: 540nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149689BDBM149689(US8975267, 30)
Affinity DataIC50: 622nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149685BDBM149685(US8975267, 7)
Affinity DataIC50: 748nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149694BDBM149694(US8975267, 36)
Affinity DataIC50: 814nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149692BDBM149692(US8975267, 34)
Affinity DataIC50: 855nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149691BDBM149691(US8975267, 33)
Affinity DataIC50: 1.55E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149687BDBM149687(US8975267, 25)
Affinity DataIC50: 2.44E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149688BDBM149688(US8975267, 29)
Affinity DataIC50: 2.94E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149695BDBM149695(US8975267, 38)
Affinity DataIC50: 2.94E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149693BDBM149693(US8975267, 35)
Affinity DataIC50: 4.55E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149682BDBM149682(US8975267, Ref. compound 3)
Affinity DataIC50: 5.00E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149682BDBM149682(US8975267, Ref. compound 3)
Affinity DataIC50: 5.00E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149683BDBM149683(US8975267, Ref. compound 4)
Affinity DataIC50: 5.00E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149683BDBM149683(US8975267, Ref. compound 4)
Affinity DataIC50: 5.00E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149685BDBM149685(US8975267, 7)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149681BDBM149681(US8975267, Ref. compound 2)
Affinity DataIC50: 5.00E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149681BDBM149681(US8975267, Ref. compound 2)
Affinity DataIC50: 5.00E+3nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149682BDBM149682(US8975267, Ref. compound 3)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149683BDBM149683(US8975267, Ref. compound 4)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149684BDBM149684(US8975267, 3)
Affinity DataIC50: 1.00E+4nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149684BDBM149684(US8975267, 3)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149680BDBM149680(US8975267, Ref. compound 1)
Affinity DataIC50: 1.00E+4nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149680BDBM149680(US8975267, Ref. compound 1)
Affinity DataIC50: 1.00E+4nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149680BDBM149680(US8975267, Ref. compound 1)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149681BDBM149681(US8975267, Ref. compound 2)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 149690BDBM149690(US8975267, 32)
Affinity DataIC50: 1.00E+4nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 47183BDBM47183(US8975267, 16)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent

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