Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 6900
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158161(US9029360, 4)
Affinity DataIC50:  33nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158163(US9029360, 6)
Affinity DataIC50:  43nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158167(US9029360, 10)
Affinity DataIC50:  59nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158170(US9029360, 13)
Affinity DataIC50:  63nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158168(US9029360, 11)
Affinity DataIC50:  66nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158162(US9029360, 5)
Affinity DataIC50:  110nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158176(US9029360, 19)
Affinity DataIC50:  128nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158158(US9029360, 1)
Affinity DataIC50:  146nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158169(US9029360, 12)
Affinity DataIC50:  148nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158159(US9029360, 2)
Affinity DataIC50:  230nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158175(US9029360, 18)
Affinity DataIC50:  235nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158164(US9029360, 7)
Affinity DataIC50:  340nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158174(US9029360, 17)
Affinity DataIC50:  550nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158171(US9029360, 14)
Affinity DataIC50:  603nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158172(US9029360, 15)
Affinity DataIC50:  692nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158173(US9029360, 16)
Affinity DataIC50:  1.29E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158160(US9029360, 3)
Affinity DataIC50:  1.39E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158166(US9029360, 9)
Affinity DataIC50:  1.42E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158165(US9029360, 8)
Affinity DataIC50:  1.55E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158166(US9029360, 9)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158167(US9029360, 10)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158168(US9029360, 11)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158169(US9029360, 12)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158170(US9029360, 13)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158171(US9029360, 14)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158172(US9029360, 15)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158173(US9029360, 16)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158165(US9029360, 8)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158164(US9029360, 7)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158163(US9029360, 6)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158161(US9029360, 4)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158160(US9029360, 3)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158159(US9029360, 2)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158158(US9029360, 1)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158174(US9029360, 17)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158162(US9029360, 5)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent