Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 7030
TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 47224BDBM47224(US9073917, 2-inventive)
Affinity DataIC50: 1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 47224BDBM47224(US9073917, 2-inventive)
Affinity DataIC50: 1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167515BDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167510BDBM167510(US9073917, 7- comparative)
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167515BDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167510BDBM167510(US9073917, 7- comparative)
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167506BDBM167506(US9073917, 1-inventive)
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167506BDBM167506(US9073917, 1-inventive)
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167507BDBM167507(US9073917, 4- comparative)
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167508BDBM167508(US9073917, 5- comparative)
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167512BDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50: 8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167513BDBM167513(US9073917, 10- comparative)
Affinity DataIC50: 9nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167516BDBM167516(US9073917, 13- comparative)
Affinity DataIC50: 10nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167516BDBM167516(US9073917, 13- comparative)
Affinity DataIC50: 11nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167509BDBM167509(US9073917, 6- comparative)
Affinity DataIC50: 13nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167512BDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50: 15nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167511BDBM167511(US9073917, 8- comparative)
Affinity DataIC50: 21nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167513BDBM167513(US9073917, 10- comparative)
Affinity DataIC50: 22nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167508BDBM167508(US9073917, 5- comparative)
Affinity DataIC50: 23nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 167515BDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 68nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167507BDBM167507(US9073917, 4- comparative)
Affinity DataIC50: 72nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167511BDBM167511(US9073917, 8- comparative)
Affinity DataIC50: 102nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167512BDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50: 107nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167509BDBM167509(US9073917, 6- comparative)
Affinity DataIC50: 109nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 60452BDBM60452(US9073917, 3-comparative)
Affinity DataIC50: 900nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 167512BDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50: 1.76E+3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 60452BDBM60452(US9073917, 3-comparative)
Affinity DataIC50: 3.80E+3nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent