Compile Data Set for Download or QSAR
Report error Found 118 Enz. Inhib. hit(s) with all data for entry = 7295
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186994BDBM186994(US9169209, Table 3, Compound 25)
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186981BDBM186981(US9169209, Table 3, Compound 12)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187028BDBM187028(US9169209, Table 3, Compound 61)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187007BDBM187007(US9169209, Table 3, Compound 39)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187065BDBM187065(US9169209, Table 3, Compound 98)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187005BDBM187005(US9169209, Table 3, Compound 37)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187023BDBM187023(US9169209, Table 3, Compound 56)
Affinity DataIC50: 2.45nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187032BDBM187032(US9169209, Table 3, Compound 65)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186984BDBM186984(US9169209, Table 3, Compound 15)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187012BDBM187012(US9169209, Table 3, Compound 44)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187008BDBM187008(US9169209, Table 3, Compound 40)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 60806BDBM60806(US9169209, Table 3, Compound 3)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187026BDBM187026(US9169209, Table 3, Compound 59)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187049BDBM187049(US9169209, Table 3, Compound 82)
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187045BDBM187045(US9169209, Table 3, Compound 78)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187003BDBM187003(US9169209, Table 3, Compound 34)
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186979BDBM186979(US9169209, Table 3, Compound 10)
Affinity DataIC50: 3.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186970BDBM186970(US9169209, Table 3, Compound 1)
Affinity DataIC50: 3.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186977BDBM186977(US9169209, Table 3, Compound 8)
Affinity DataIC50: 3.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 50439677BDBM50439677(CHEMBL2417790 | US9169209, Table 3, Compound 55)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187024BDBM187024(US9169209, Table 3, Compound 57)
Affinity DataIC50: 4.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187058BDBM187058(US9169209, Table 3, Compound 91)
Affinity DataIC50: 4.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187069BDBM187069(US9169209, Table 3, Compound 102)
Affinity DataIC50: 4.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187071BDBM187071(US9169209, Table 3, Compound 104)
Affinity DataIC50: 4.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186988BDBM186988(US9169209, Table 3, Compound 19)
Affinity DataIC50: 4.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187013BDBM187013(US9169209, Table 3, Compound 45)
Affinity DataIC50: 4.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187077BDBM187077(US9169209, Table 3, Compound 110)
Affinity DataIC50: 5.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186978BDBM186978(US9169209, Table 3, Compound 9)
Affinity DataIC50: 5.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187001BDBM187001(US9169209, Table 3, Compound 32)
Affinity DataIC50: 5.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187038BDBM187038(US9169209, Table 3, Compound 71)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187036BDBM187036(US9169209, Table 3, Compound 69)
Affinity DataIC50: 5.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187021BDBM187021(US9169209, Table 3, Compound 53)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187083BDBM187083(US9169209, Table 3, Compound 116)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187041BDBM187041(US9169209, Table 3, Compound 74)
Affinity DataIC50: 6.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187067BDBM187067(US9169209, Table 3, Compound 100)
Affinity DataIC50: 6.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187078BDBM187078(US9169209, Table 3, Compound 111)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187025BDBM187025(US9169209, Table 3, Compound 58)
Affinity DataIC50: 7.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187059BDBM187059(US9169209, Table 3, Compound 92)
Affinity DataIC50: 7.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187084BDBM187084(US9169209, Table 3, Compound 117)
Affinity DataIC50: 7.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187073BDBM187073(US9169209, Table 3, Compound 106)
Affinity DataIC50: 7.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187052BDBM187052(US9169209, Table 3, Compound 85)
Affinity DataIC50: 7.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187029BDBM187029(US9169209, Table 3, Compound 62)
Affinity DataIC50: 7.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187011BDBM187011(US9169209, Table 3, Compound 43)
Affinity DataIC50: 7.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186992BDBM186992(US9169209, Table 3, Compound 23)
Affinity DataIC50: 7.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186999BDBM186999(US9169209, Table 3, Compound 30)
Affinity DataIC50: 7.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187074BDBM187074(US9169209, Table 3, Compound 107)
Affinity DataIC50: 7.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 186996BDBM186996(US9169209, Table 3, Compound 27)
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187043BDBM187043(US9169209, Table 3, Compound 76)
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187006BDBM187006(US9169209, Table 3, Compound 38)
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 187037BDBM187037(US9169209, Table 3, Compound 70)
Affinity DataIC50: 8.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

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