Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 7593
TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156378BDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156377BDBM156377(US9018381, 2 | US9248140, 2)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 204937BDBM204937(US9248140, 21)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 204936BDBM204936(US9248140, 20)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156403BDBM156403(US9018381, 26 | US9248140, 26)
Affinity DataIC50: 0.400nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156402BDBM156402(US9018381, 25 | US9248140, 25)
Affinity DataIC50: 0.400nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156401BDBM156401(US9018381, 24 | US9248140, 24)
Affinity DataIC50: 0.400nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156403BDBM156403(US9018381, 26 | US9248140, 26)
Affinity DataIC50: 0.5nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 204937BDBM204937(US9248140, 21)
Affinity DataIC50: 0.5nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156380BDBM156380(US9018381, 4 | US9248140, 4)
Affinity DataIC50: 0.5nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156399BDBM156399(US9018381, 22 | US9248140, 22)
Affinity DataIC50: 0.600nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156387BDBM156387(US9018381, 10 | US9248140, 10)
Affinity DataIC50: 0.700nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156393BDBM156393(US9018381, 16 | US9248140, 16)
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156380BDBM156380(US9018381, 4 | US9248140, 4)
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156382BDBM156382(US9018381, 5 | US9248140, 5)
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156386BDBM156386(US9018381, 9 | US9248140, 9)
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156385BDBM156385(US9018381, 8 | US9248140, 8)
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156393BDBM156393(US9018381, 16 | US9248140, 16)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156392BDBM156392(US9018381, 15 | US9248140, 15)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156394BDBM156394(US9018381, 18 | US9018381, 17 | US9248140, 18)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156400BDBM156400(US9018381, 23 | US9248140, 23)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156400BDBM156400(US9018381, 23 | US9248140, 23)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 204936BDBM204936(US9248140, 20)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156377BDBM156377(US9018381, 2 | US9248140, 2)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156376BDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156376BDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156407BDBM156407(US9018381, 30 | US9248140, 30)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156407BDBM156407(US9018381, 30 | US9248140, 30)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156385BDBM156385(US9018381, 8 | US9248140, 8)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156384BDBM156384(US9018381, 7 | US9248140, 7)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156383BDBM156383(US9018381, 6 | US9248140, 6)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156387BDBM156387(US9018381, 10 | US9248140, 10)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156386BDBM156386(US9018381, 9 | US9248140, 9)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156378BDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156382BDBM156382(US9018381, 5 | US9248140, 5)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156394BDBM156394(US9018381, 18 | US9018381, 17 | US9248140, 18)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156394BDBM156394(US9018381, 18 | US9018381, 17 | US9248140, 18)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156405BDBM156405(US9018381, 28 | US9248140, 28)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156401BDBM156401(US9018381, 24 | US9248140, 24)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156384BDBM156384(US9018381, 7 | US9248140, 7)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156402BDBM156402(US9018381, 25 | US9248140, 25)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156383BDBM156383(US9018381, 6 | US9248140, 6)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156392BDBM156392(US9018381, 15 | US9248140, 15)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156389BDBM156389(US9018381, 12 | US9248140, 12)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156388BDBM156388(US9018381, 11 | US9248140, 11)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156389BDBM156389(US9018381, 12 | US9248140, 12)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156399BDBM156399(US9018381, 22 | US9248140, 22)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156388BDBM156388(US9018381, 11 | US9248140, 11)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156405BDBM156405(US9018381, 28 | US9248140, 28)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 156394BDBM156394(US9018381, 18 | US9018381, 17 | US9248140, 18)
Affinity DataIC50: 7nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

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