Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 7622
TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120116BDBM120116(US8697715, 209 | US9259470, 209)
Affinity DataIC50: 0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120117BDBM120117(US8697715, 250 | US9259470, 250)
Affinity DataIC50: 1.60nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120119BDBM120119(US8697715, 270 | US9259470, 270)
Affinity DataIC50: 2.20nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120118BDBM120118(US8697715, 266 | US9259470, 266)
Affinity DataIC50: 2.40nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120127BDBM120127(US8697715, Beta | US9259470, Beta)
Affinity DataIC50: 2.60nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120113BDBM120113(US8697715, 172 | US9259470, 172)
Affinity DataIC50: 2.90nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120111BDBM120111(US8697715, 166 | US9259470, 166)
Affinity DataIC50: 2.90nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120103BDBM120103(US8697715, 87 | US9259470, 87)
Affinity DataIC50: 3nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120094BDBM120094(US8697715, 21 | US9259470, 21)
Affinity DataIC50: 3nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 206343BDBM206343(US9259470, 167)
Affinity DataIC50: 3.10nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120087BDBM120087(US8697715, 2 | US9259470, 2)
Affinity DataIC50: 3.20nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120102BDBM120102(US8697715, 68 | US9259470, 68)
Affinity DataIC50: 3.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120095BDBM120095(US8697715, 39 | US9259470, 39 | US10525036, Exampl...)
Affinity DataIC50: 3.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120089BDBM120089(US8697715, 4 | US9259470, 4)
Affinity DataIC50: 3.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120107BDBM120107(US8697715, 120 | US9259470, 120)
Affinity DataIC50: 3.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120086BDBM120086(US8697715, 1 | US9259470, 1)
Affinity DataIC50: 3.90nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120115BDBM120115(US8697715, 185 | US9259470, 185)
Affinity DataIC50: 3.90nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120088BDBM120088(US8697715, 3 | US9259470, 3)
Affinity DataIC50: 4nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120125BDBM120125(US8697715, 305 | US9259470, 305)
Affinity DataIC50: 4nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120108BDBM120108(US8697715, 134 | US9259470, 134)
Affinity DataIC50: 5.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120114BDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50: 5.70nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120101BDBM120101(US8697715, 65 | US9259470, 65)
Affinity DataIC50: 6.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120096BDBM120096(US8697715, 42 | US9259470, 42)
Affinity DataIC50: 6.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120120BDBM120120(US8697715, 289 | US9259470, 289)
Affinity DataIC50: 8.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120110BDBM120110(US8697715, 157 | US9259470, 157)
Affinity DataIC50: 8.70nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120123BDBM120123(US8697715, 293 | US9259470, 293)
Affinity DataIC50: 9.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120105BDBM120105(US8697715, 103 | US9259470, 103)
Affinity DataIC50: 10.4nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120097BDBM120097(US8697715, 50 | US9259470, 50)
Affinity DataIC50: 11.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120122BDBM120122(US8697715, 291 | US9259470, 291)
Affinity DataIC50: 12.1nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120090BDBM120090(US8697715, 11 | US9259470, 11)
Affinity DataIC50: 13.6nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120109BDBM120109(US8697715, 139 | US9259470, 139)
Affinity DataIC50: 13.7nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120099BDBM120099(US8697715, 58 | US9259470, 58)
Affinity DataIC50: 13.9nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120124BDBM120124(US8697715, 295 | US9259470, 295)
Affinity DataIC50: 14.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120092BDBM120092(US8697715, 14 | US9259470, 14)
Affinity DataIC50: 15.6nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120121BDBM120121(US8697715, 290 | US9259470, 290)
Affinity DataIC50: 15.8nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120106BDBM120106(US8697715, 109 | US9259470, 109)
Affinity DataIC50: 15.9nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120098BDBM120098(US8697715, 57 | US9259470, 57)
Affinity DataIC50: 35.7nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120104BDBM120104(US8697715, 102 | US9259470, 102)
Affinity DataIC50: 39.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120091BDBM120091(US8697715, 12 | US9259470, 12)
Affinity DataIC50: 51.8nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120100BDBM120100(US8697715, 60 | US9259470, 60)
Affinity DataIC50: 53nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120093BDBM120093(US8697715, 20 | US9259470, 20)
Affinity DataIC50: 146nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 120126BDBM120126(US8697715, Alpha | US9259470, Alpha)
Affinity DataIC50: 249nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent