Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 7690
TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210877BDBM210877(US9290467, 47)
Affinity DataIC50: 1.60nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210881BDBM210881(US9290467, 51)
Affinity DataIC50: 1.60nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210873BDBM210873(US9290467, 43)
Affinity DataIC50: 3.10nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210875BDBM210875(US9290467, 45)
Affinity DataIC50: 4.30nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210871BDBM210871(US9290467, 41)
Affinity DataIC50: 5.20nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210870BDBM210870(US9290467, 40)
Affinity DataIC50: 6.90nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210867BDBM210867(US9290467, 37)
Affinity DataIC50: 9nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210864BDBM210864(US9290467, 34)
Affinity DataIC50: 9nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210874BDBM210874(US9290467, 44)
Affinity DataIC50: 9.20nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210835BDBM210835(US9290467, 5)
Affinity DataIC50: 9.60nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210839BDBM210839(US9290467, 9)
Affinity DataIC50: 10nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210868BDBM210868(US9290467, 38)
Affinity DataIC50: 10nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210840BDBM210840(US9290467, 10)
Affinity DataIC50: 10.3nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210847BDBM210847(US9290467, 17)
Affinity DataIC50: 10.4nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210858BDBM210858(US9290467, 28)
Affinity DataIC50: 11nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210846BDBM210846(US9290467, 16)
Affinity DataIC50: 11.4nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210841BDBM210841(US9290467, 11)
Affinity DataIC50: 11.6nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210861BDBM210861(US9290467, 31)
Affinity DataIC50: 12nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210859BDBM210859(US9290467, 29)
Affinity DataIC50: 13nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210880BDBM210880(US9290467, 50)
Affinity DataIC50: 13.5nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210834BDBM210834(US9290467, 4)
Affinity DataIC50: 13.8nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210857BDBM210857(US9290467, 27)
Affinity DataIC50: 16nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210862BDBM210862(US9290467, 32)
Affinity DataIC50: 16nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210879BDBM210879(US9290467, 49)
Affinity DataIC50: 18.3nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210865BDBM210865(US9290467, 35)
Affinity DataIC50: 23nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210838BDBM210838(US9290467, 8)
Affinity DataIC50: 24.8nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210872BDBM210872(US9290467, 42)
Affinity DataIC50: 25.5nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210849BDBM210849(US9290467, 19)
Affinity DataIC50: 26nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210869BDBM210869(US9290467, 39)
Affinity DataIC50: 26.2nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210836BDBM210836(US9290467, 6)
Affinity DataIC50: 32nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210850BDBM210850(US9290467, 20)
Affinity DataIC50: 47.7nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210866BDBM210866(US9290467, 36)
Affinity DataIC50: 50nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210853BDBM210853(US9290467, 23)
Affinity DataIC50: 50nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210876BDBM210876(US9290467, 46)
Affinity DataIC50: 54nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210851BDBM210851(US9290467, 21)
Affinity DataIC50: 54nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210848BDBM210848(US9290467, 18)
Affinity DataIC50: 54.7nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210863BDBM210863(US9290467, 33)
Affinity DataIC50: 73nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210833BDBM210833(US9290467, 3)
Affinity DataIC50: 77nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210831BDBM210831(US9290467, 1)
Affinity DataIC50: 88.5nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210837BDBM210837(US9290467, 7)
Affinity DataIC50: 96.2nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210852BDBM210852(US9290467, 22)
Affinity DataIC50: 118nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210878BDBM210878(US9290467, 48)
Affinity DataIC50: 139nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210854BDBM210854(US9290467, 25 | US9290467, 26 | US9290467, 24)
Affinity DataIC50: 139nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210854BDBM210854(US9290467, 25 | US9290467, 26 | US9290467, 24)
Affinity DataIC50: 164nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210845BDBM210845(US9290467, 15)
Affinity DataIC50: 168nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210860BDBM210860(US9290467, 30)
Affinity DataIC50: 181nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210832BDBM210832(US9290467, 2)
Affinity DataIC50: 230nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210854BDBM210854(US9290467, 25 | US9290467, 26 | US9290467, 24)
Affinity DataIC50: 236nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210842BDBM210842(US9290467, 12)
Affinity DataIC50: 878nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 210843BDBM210843(US9290467, 13)
Affinity DataIC50: 948nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

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