Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 424
TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106287BDBM50106287(CHEMBL3598148 | US9550771, Example 17)
Affinity DataEC50:  2nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106285BDBM50106285(CHEMBL3596279 | US9550771, Example 91)
Affinity DataEC50:  2nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268455BDBM268455(4-[8-chloro-3-(2-chloro-6- cyclopropyl- benzoyl)im...)
Affinity DataEC50:  2nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268454BDBM268454(4-[3-(2-chloro-6-morpholino- benzoyl)imidazo[1,5-a...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268417BDBM268417(4-[3-(2,6- dichlorobenzoyl)imidazo[1,5 a]pyridin-1...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268449BDBM268449(4-[6-(azetidine-1-carbonyl)-3-(2- chloro-6-cyclopr...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268413BDBM268413(2-hydroxy-4-[3-[2- (trifluoromethyl)benzoyl]imidaz...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268425BDBM268425(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268439BDBM268439(4-[3-(2- cyclopropylbenzoyl)imidazo[1,5- a]pyridin...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268483BDBM268483(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  4nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268479BDBM268479(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  4nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268481BDBM268481(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  6nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268444BDBM268444(4-[3-(2-chloro-6-cyclopropyl- benzoyl)-6- (dimethy...)
Affinity DataEC50:  6nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268474BDBM268474(4-[3-[2-bromo-6- (trifluoromethyl)benzoyl]-5,6,7,8...)
Affinity DataEC50:  6nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268427BDBM268427(2-acetoxy-4-[3-[2-chloro-6- (trifluoromethyl)benzo...)
Affinity DataEC50:  7nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268475BDBM268475(4-[3-(2-bromo-6-chloro-benzoyl)- 5,6,7,8-tetrahydr...)
Affinity DataEC50:  7nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268469BDBM268469(4-[3-(2,6-dichlorobenzoyl)- 5,6,7,8-tetrahydroimid...)
Affinity DataEC50:  8nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268404BDBM268404(4-(3-(2-(Trifluoromethyl)benzoyl)imidazo[1,5-a]pyr...)
Affinity DataEC50:  8nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268435BDBM268435(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  9nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106288BDBM50106288(CHEMBL3598149 | US9550771, Example 28)
Affinity DataEC50:  9nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268491BDBM268491(4-[3-(2-chloro-6-cyclopropyl- benzoyl)-5,6,7,8- te...)
Affinity DataEC50:  9nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106286BDBM50106286(CHEMBL3598141 | US9550771, Example 27)
Affinity DataEC50:  10nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268482BDBM268482(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  12nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268461BDBM268461((3S,4R)-1-[8-chloro-3-(2-chloro- 6-cyclopropyl- be...)
Affinity DataEC50:  13nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268478BDBM268478(2-hydroxy-4-[3-[2-methyl-6- (trifluoromethyl)benzo...)
Affinity DataEC50:  14nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268457BDBM268457((3S,4R)-1-[3-(2-chloro-6- cyclopropyl-benzoyl)-6- ...)
Affinity DataEC50:  19nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268445BDBM268445(4-[3-(2-chloro-6-cyclopropyl- benzoyl)-6- (dimethy...)
Affinity DataEC50:  22nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268402BDBM268402(4-(3-(2,6-Dichlorobenzoyl)imidazo[1,5-a]pyridin-1-...)
Affinity DataEC50:  26nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106290BDBM50106290(CHEMBL3596276 | US9550771, Example 89)
Affinity DataEC50:  27nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268450BDBM268450(US9550771, Example 49 | (3S,4R)-1-[3-(2-chloro-6- ...)
Affinity DataEC50:  29nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106289BDBM50106289(CHEMBL3596270 | US9550771, Example 21)
Affinity DataEC50:  32nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268436BDBM268436(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  45nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268463BDBM268463(2-hydroxy-4-[3-[2- (trifluoromethyl)benzoyl]-5,6,7...)
Affinity DataEC50:  49nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268448BDBM268448(2-hydroxy-4-[3-(2- morpholinobenzoyl)imidazo[1,5- ...)
Affinity DataEC50:  50nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268456BDBM268456(1-[6-(azetidine-1-carbonyl)-3-(2- chloro-6-cyclopr...)
Affinity DataEC50:  50nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106302BDBM50106302(CHEMBL3598142 | US9550771, Example 22)
Affinity DataEC50:  58nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268450BDBM268450(US9550771, Example 49 | (3S,4R)-1-[3-(2-chloro-6- ...)
Affinity DataEC50:  63nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268459BDBM268459(1-[3-(2-chloro-6-cyclopropyl- benzoyl)-6-(3-methox...)
Affinity DataEC50:  70nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268438BDBM268438(1-[3-[2-chloro-6- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  72nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106296BDBM50106296(CHEMBL3596273 | US9550771, Example 69)
Affinity DataEC50:  77nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268406BDBM268406(1-(3-(2-chloro-6-(trifluoromethyl)benzoyl)imidazo[...)
Affinity DataEC50:  77nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268419BDBM268419(4-[6-(2,6- dichlorobenzoyl)imidazo[1,5- a]pyrimidi...)
Affinity DataEC50:  84nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106293BDBM50106293(CHEMBL3596269 | US9550771, Example 41)
Affinity DataEC50:  97nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 50106325BDBM50106325(CHEMBL3598150 | US9550771, Example 29)
Affinity DataEC50:  103nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268447BDBM268447(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  109nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268440BDBM268440(6-[3-[2-chloro-6- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  111nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268446BDBM268446(1-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  139nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268426BDBM268426(3-chloro-4-[3-[2-chloro-6- (trifluoromethyl)benzoy...)
Affinity DataEC50:  171nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268407BDBM268407(4-[3-[2- (trifluoromethyl)benzoyl]imidazo [1,5-a]p...)
Affinity DataEC50:  179nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268416BDBM268416(3,5-difluoro-4-[3-[2- (trifluoromethyl)benzoyl]imi...)
Affinity DataEC50:  189nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

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