Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 107
TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175039BDBM175039(US9688678, 11 (+)-3-(2-ethoxy-5-methoxyphenyl)-1-(...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175064BDBM175064(US9688678, 25 (+)-3-(2-ethoxy-5-methoxy-phenyl)-1-...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175037BDBM175037(US9688678, 9A (+)-3-(2-ethoxy-3-pyridyl)-1-[(5-met...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175060BDBM175060(US9688678, 21 (+-)-3-(2,5-dimethoxyphenyl)-1-[(5-m...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175058BDBM175058(US9688678, 19 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-3...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175057BDBM175057(US9688678, 18A (+)-3-(2-methoxyphenyl)-1-[(5-metho...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175212BDBM175212(US9688678, 34 (3S)-1-[(5-chloro-2-pyridyl)sulfonyl...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175056BDBM175056(US9688678, 18 (+-)3-(2-methoxyphenyl)-1-[(5-methox...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175055BDBM175055(US9688678, 17B (+)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175054BDBM175054(US9688678, 17 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 174904BDBM174904(US9688678, 1A (+)-3-(2-ethoxy-5-methoxy-phenyl)-1-...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175038BDBM175038(US9688678, 10 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175036BDBM175036(US9688678, 9 (+-)-3-(2-ethoxy-3-pyridyl)-1-[(5-met...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175061BDBM175061(US9688678, 22 (+-)-3-(2-methoxy-3-pyridyl)-1-[(5-m...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175059BDBM175059(US9688678, 20 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-3...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175069BDBM175069(US9688678, 30 (+-)-3-[2-(1,1-difluoroethyl)-3-pyri...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 174900BDBM174900(US9688678, 1 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1-...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175068BDBM175068(US9688678, 29 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175067BDBM175067(US9688678, 28 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175066BDBM175066(US9688678, 27 (+-)-3-(2-ethoxy-3-pyridyl)-1-[(5-me...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175065BDBM175065(US9688678, 26 (+-)-3-(2-methoxyphenyl)-1-[(5-metho...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175062BDBM175062(US9688678, 23 (+)-3-(2-methoxyphenyl)-1-[(5-methox...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175035BDBM175035(US9688678, 8 (+-)-3-(2-ethoxyphenyl)-1-[(5-methoxy...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175034BDBM175034(US9688678, 7 (+-)-3-(2-ethoxy-4-fluoro-phenyl)-1-[...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175032BDBM175032(US9688678, 5 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1-...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175211BDBM175211(US9688678, 33 (3S)-3-(2-ethoxy-5-methoxy-phenyl)-3...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175074BDBM175074(US9688678, 31 (3S)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175053BDBM175053(US9688678, 16 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175052BDBM175052(US9688678, 15 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-3...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175048BDBM175048(US9688678, 14 (+-)-1-(4-cyanophenyl)sulfonyl-3-(2-...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175040BDBM175040(US9688678, 12 (+-)-3-(2-ethoxy-3-pyridyl)-1-(4-met...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175063BDBM175063(US9688678, 24 (+)-1-(2,4-dimethoxyphenyl)sulfonyl-...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175032BDBM175032(US9688678, 5 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1-...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 174970BDBM174970(US9688678, 3 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-3-...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 174969BDBM174969(US9688678, 2 (+-)-1-(2,4-dimethoxyphenyl)sulfonyl-...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 175210BDBM175210(US9688678, 32 (3S)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandChemical structure of BindingDB Monomer ID 174968BDBM174968(US9688678, 1B (−)-3-(2-ethoxy-5-methoxy-phen...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent