Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 1927
TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323669BDBM323669((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 0.600nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323644BDBM323644((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 1.40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323668BDBM323668(N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- et...)
Affinity DataIC50: 1.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323626BDBM323626(US10188653, Example 15 | US9789110, 15)
Affinity DataIC50: 2.40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323638BDBM323638((R)-N-benzyl-2-(3-(2- ethoxyphenoxy)piperidin- 1-y...)
Affinity DataIC50: 4.30nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 276749BDBM276749(WO2015140658, Example 19.21 | US10188653, Example ...)
Affinity DataIC50: 7.90nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323662BDBM323662((R)-(3,3-difluoroazetidin- 1-yl)(2-(3-(2- ethoxyph...)
Affinity DataIC50: 7.90nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323602BDBM323602(US10188653, Example 8 | US9789110, 8)
Affinity DataIC50: 9.70nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323655BDBM323655((R)-N-cyclobutyl-2-(3-(2- ethoxyphenoxy)piperidin-...)
Affinity DataIC50: 10.7nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323634BDBM323634((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(iso...)
Affinity DataIC50: 10.8nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323652BDBM323652((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(iso...)
Affinity DataIC50: 11.1nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323647BDBM323647((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(oxa...)
Affinity DataIC50: 11.2nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323649BDBM323649((R)-N-(4-amino-2-methyl- 4-oxobutan-2-yl)-2-(3-(2-...)
Affinity DataIC50: 12.2nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323640BDBM323640((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 14.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323667BDBM323667((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 15.7nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323635BDBM323635((R)-N-(cyclopropylmethyl)- 2-(3-(2- ethoxyphenoxy)...)
Affinity DataIC50: 18.6nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323646BDBM323646(((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptan-5- yl)(2...)
Affinity DataIC50: 21.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323650BDBM323650((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(pyr...)
Affinity DataIC50: 22.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323632BDBM323632((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 22.6nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323664BDBM323664((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 24.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323643BDBM323643((R)-azetidin-1-yl(2-(3-(2- ethoxyphenoxy)piperidin...)
Affinity DataIC50: 26.7nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323663BDBM323663((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(2-(...)
Affinity DataIC50: 29.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323641BDBM323641((R)-N-(2-(1H-1,2,4-triazol- 1-yl)ethyl)-2-(3-(2- e...)
Affinity DataIC50: 32.4nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323653BDBM323653((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(pyr...)
Affinity DataIC50: 33.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323637BDBM323637((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...)
Affinity DataIC50: 34.9nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323595BDBM323595(US10188653, Example 4 | US9789110, 4)
Affinity DataIC50: 35nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323612BDBM323612(US10188653, Example 9 | US9789110, 9)
Affinity DataIC50: 38.1nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323624BDBM323624(US10188653, Example 13 | US9789110, 13)
Affinity DataIC50: 45.2nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323645BDBM323645(2-((R)-3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((R...)
Affinity DataIC50: 46.7nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323627BDBM323627(US10188653, Example 16 | US9789110, 16)
Affinity DataIC50: 47.7nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323659BDBM323659((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(3-(...)
Affinity DataIC50: 53.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323623BDBM323623(US10188653, Example 12 | US9789110, 12)
Affinity DataIC50: 62.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323596BDBM323596(US10188653, Example 5 | US9789110, 5)
Affinity DataIC50: 66.6nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323660BDBM323660((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((5...)
Affinity DataIC50: 68nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323625BDBM323625(US10188653, Example 14 | US9789110, 14)
Affinity DataIC50: 76.6nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323621BDBM323621(US10188653, Example 10 | US9789110, 10)
Affinity DataIC50: 87.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323592BDBM323592(US10188653, Example 3 | US9789110, 3)
Affinity DataIC50: 88.4nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323589BDBM323589(US10188653, Example 1 | US9789110, 1)
Affinity DataIC50: 91.6nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 347385BDBM347385((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(2- ...)
Affinity DataIC50: 102nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323658BDBM323658((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N,N- d...)
Affinity DataIC50: 104nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323622BDBM323622(US10188653, Example 11 | US9789110, 11)
Affinity DataIC50: 122nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323648BDBM323648(2-((R)-3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((S...)
Affinity DataIC50: 122nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323591BDBM323591(US10188653, Example 2 | US9789110, 2)
Affinity DataIC50: 123nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323636BDBM323636((R)-N-(2-amino-2- iminoethyl)-2-(3-(2- ethoxypheno...)
Affinity DataIC50: 124nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323661BDBM323661((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)-N- (2-...)
Affinity DataIC50: 144nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323656BDBM323656((R)-N-(3-amino-3- oxopropyl)-2-(3-(2- ethoxyphenox...)
Affinity DataIC50: 149nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323601BDBM323601(US10188653, Example 7 | US9789110, 7)
Affinity DataIC50: 149nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323630BDBM323630((R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)...)
Affinity DataIC50: 156nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323629BDBM323629((R)-4-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)pyr...)
Affinity DataIC50: 165nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 323666BDBM323666((S)-1-(2-((R)-3-(2- ethoxyphenoxy)piperidin- 1-yl)...)
Affinity DataIC50: 170nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

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