Compile Data Set for Download or QSAR
Report error Found 170 Enz. Inhib. hit(s) with all data for entry = 10037
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510127BDBM510127(WO2021250648, Example 79 | WO2021250648, Example 9...)
Affinity DataIC50: 1nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510063BDBM510063(WO2021250648, Example 15 | N-[(2S)-1-({(1S)-1-Cyan...)
Affinity DataIC50: 2nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 496902BDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataIC50: 3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510129BDBM510129(WO2021250648, Example 81 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510132BDBM510132(WO2021250648, Example 84 | (1R,2S,5S)-N-{(1 S)-1-C...)
Affinity DataIC50: 3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510127BDBM510127(WO2021250648, Example 79 | WO2021250648, Example 9...)
Affinity DataIC50: 3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510140BDBM510140(WO2021250648, Example 92 | 3-Methyl-N-[(4-methylph...)
Affinity DataIC50: 4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510133BDBM510133(WO2021250648, Example 85 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510125BDBM510125(WO2021250648, Example 77 | 3-Methyl-N-(trifluoroac...)
Affinity DataIC50: 4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510126BDBM510126(WO2021250648, Example 78 | (1R,2S,5S)-N-{(1 S)-1-C...)
Affinity DataIC50: 5nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510068BDBM510068(WO2021250648, Example 20 | N-[(2S)-1-({(1 S)-1-Cya...)
Affinity DataIC50: 5nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510136BDBM510136(WO2021250648, Example 88 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 6nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510139BDBM510139(WO2021250648, Example 91 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 7nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510137BDBM510137(WO2021250648, Example 89 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 7nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510139BDBM510139(WO2021250648, Example 91 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataEC50:  11nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510142BDBM510142(WO2021250648, Example 94 | (1R,2S,5S)-N-{(1 S)-1-C...)
Affinity DataIC50: 11nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510145BDBM510145(WO2021250648, Example 97 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 11nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510048BDBM510048(WO2021250648, Example 1 | (1R,2S,5S)-N-{(1S)-1-Cya...)
Affinity DataIC50: 13nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510141BDBM510141(WO2021250648, Example 93 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 14nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510138BDBM510138(WO2021250648, Example 90 | (1R,2S,5S)-N-{(1 S)-1-C...)
Affinity DataIC50: 15nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510134BDBM510134(WO2021250648, Example 86 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataIC50: 16nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510123BDBM510123(WO2021250648, Example 75 | (2S,4R)-4-tert-Butyl-N-...)
Affinity DataIC50: 17nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510064BDBM510064(WO2021250648, Example 16 | N-[(2S)-1-({(1S)-1- Cya...)
Affinity DataIC50: 18nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510140BDBM510140(WO2021250648, Example 92 | 3-Methyl-N-[(4-methylph...)
Affinity DataEC50:  19nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510066BDBM510066(WO2021250648, Example 18 | N-[(2S)-1-({(1S)-1-Cyan...)
Affinity DataIC50: 19nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510071BDBM510071(WO2021250648, Example 23 | N-[(2S)-1-({(1S)-1-Cyan...)
Affinity DataIC50: 21nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510135BDBM510135(WO2021250648, Example 87 | US11351149, Example 87)
Affinity DataIC50: 21nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510054BDBM510054(WO2021250648, Example 6 | N-[(2S)-1-({(1S)-1-Cyano...)
Affinity DataIC50: 23nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510086BDBM510086(WO2021250648, Example 38 | US11351149, Example 38)
Affinity DataIC50: 23nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510101BDBM510101(WO2021250648, Example 53 | US11351149, Example 53)
Affinity DataIC50: 25nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 496896BDBM496896(science.abl4784, 2 | WO2021250648, Example 4 | US1...)
Affinity DataIC50: 26nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510110BDBM510110(WO2021250648, Example 62 | US11351149, Example 62)
Affinity DataIC50: 29nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510100BDBM510100(WO2021250648, Example 52 | US11351149, Example 52)
Affinity DataIC50: 32nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510109BDBM510109(WO2021250648, Example 61 | US11351149, Example 61)
Affinity DataIC50: 34nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510128BDBM510128(WO2021250648, Example 80 | N-(Trifluoroacetyl)-L-v...)
Affinity DataIC50: 37nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510112BDBM510112(WO2021250648, Example 64 | US11351149, Example 64)
Affinity DataIC50: 38nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510137BDBM510137(WO2021250648, Example 89 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataEC50:  40nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510115BDBM510115(WO2021250648, Example 67 | US11351149, Example 67)
Affinity DataIC50: 41nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510102BDBM510102(WO2021250648, Example 54 | US11351149, Example 54)
Affinity DataIC50: 49nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510136BDBM510136(WO2021250648, Example 88 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataEC50:  50nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510105BDBM510105(WO2021250648, Example 57 | US11351149, Example 57)
Affinity DataIC50: 52nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510065BDBM510065(WO2021250648, Example 17 | N-[(2S)-1-({(1S)-1-Cyan...)
Affinity DataIC50: 53nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 509871BDBM509871(US11124497, Compound 405 | US11524940, Compound 40...)
Affinity DataIC50: 56nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510070BDBM510070(WO2021250648, Example 22 | N-[(2S)-1-({(1 S)-1-Cya...)
Affinity DataIC50: 66nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510081BDBM510081(WO2021250648, Example 33 | US11351149, Example 33)
Affinity DataIC50: 68nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510114BDBM510114(WO2021250648, Example 66 | US11351149, Example 66)
Affinity DataIC50: 73nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510082BDBM510082(WO2021250648, Example 34 | US11351149, Example 34)
Affinity DataIC50: 74nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 496902BDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataEC50:  75nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510127BDBM510127(WO2021250648, Example 79 | WO2021250648, Example 9...)
Affinity DataEC50:  80nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 510145BDBM510145(WO2021250648, Example 97 | (1R,2S,5S)-N-{(1S)-1-Cy...)
Affinity DataEC50:  82nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

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