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Target
Mu-type opioid receptor [N127C]
Ligand
BDBM579497
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
180±n/a nM
Citation
 Shoichet, BK; Lin, H; Gmeiner, P; Manglik, A; Kobilka, B; Roth, BL; Dengler, DG Mu opioid receptor modulators US Patent  US11484525 Publication Date 11/1/2022 
Target
Name:
Mu-type opioid receptor [N127C]
Synonyms:
MOR1 | OPRM1 | OPRM_HUMAN
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44778.55
Organism:
Homo sapiens (Human)
Description:
P35372 [N127C]
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVCYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM579497
Synonyms:
US11484525, Compound DD-35D | US11484525, Compound DD-35L
Type:
Small organic molecule
Emp. Form.:
C20H29N3OS
Mol. Mass.:
359.529
SMILES:
CN(C)C(CNC(=O)NC(C)(C)Cc1ccsc1)Cc1ccccc1
Structure:
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