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Target
Beta-2 adrenergic receptor
Ligand
BDBM50086673
Substrate
n/a
Meas. Tech.
ChEMBL_38611 (CHEMBL652294)
Ki
23±n/a nM
Citation
 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A (1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents. Bioorg Med Chem Lett 10:465-8 (2000) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Dog
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50086673
Synonyms:
8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1,4]thiazin-3-one | CHEMBL140908
Type:
Small organic molecule
Emp. Form.:
C15H22N2O3S
Mol. Mass.:
310.412
SMILES:
CC(C)(C)NCC(O)COc1cccc2NC(=O)CSc12
Structure:
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