Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50536910
Substrate
n/a
Meas. Tech.
ChEMBL_1935006 (CHEMBL4480765)
Ki
272±n/a nM
Citation
 Leleu-Chavain, N; Baudelet, D; Heloire, VM; Rocha, DE; Renault, N; Barczyk, A; Djouina, M; Body-Malapel, M; Carato, P; Millet, R Benzo[d]thiazol-2(3H)-ones as new potent selective CB Eur J Med Chem 165:347-362 (2019) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50536910
Synonyms:
CHEMBL4533329
Type:
Small organic molecule
Emp. Form.:
C23H31NO2S
Mol. Mass.:
385.563
SMILES:
CCCCCn1c2ccc(cc2sc1=O)C(O)C12CC3CC(CC(C3)C1)C2 |TLB:20:21:19.18.24:25,THB:22:21:18:24.23.25,22:23:20.21.26:18,20:19:21.26.22:25|
Structure:
Search PDB for entries with ligand similarity: