Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50536912
Substrate
n/a
Meas. Tech.
ChEMBL_1935007 (CHEMBL4480766)
Ki
>1000±n/a nM
Citation
 Leleu-Chavain, N; Baudelet, D; Heloire, VM; Rocha, DE; Renault, N; Barczyk, A; Djouina, M; Body-Malapel, M; Carato, P; Millet, R Benzo[d]thiazol-2(3H)-ones as new potent selective CB Eur J Med Chem 165:347-362 (2019) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50536912
Synonyms:
CHEMBL4518631
Type:
Small organic molecule
Emp. Form.:
C21H25NO2S
Mol. Mass.:
355.494
SMILES:
CC(C)n1c2ccc(cc2sc1=O)C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:18:19:17.16.22:23,THB:20:19:16:22.21.23,20:21:18.19.24:16,18:17:19.24.20:23|
Structure:
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