Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50138434
Substrate
n/a
Meas. Tech.
ChEBML_148090
Ki
1±n/a nM
Citation
 Dardonville, C; Jagerovic, N; Callado, LF; Meana, JJ Fentanyl derivatives bearing aliphatic alkaneguanidinium moieties: a new series of hybrid molecules with significant binding affinity for mu-opioid receptors and I2-imidazoline binding sites. Bioorg Med Chem Lett 14:491-3 (2003) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Human
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50138434
Synonyms:
CHEMBL147044 | N-(6-Guanidino-hexyl)-N-(1-phenethyl-piperidin-4-yl)-propionamide
Type:
Small organic molecule
Emp. Form.:
C23H39N5O
Mol. Mass.:
401.5887
SMILES:
CCC(=O)N(CCCCCCNC(N)=N)C1CCN(CCc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: