Reaction Details Report a problem with these data
Target
Group IIE secretory phospholipase A2
Ligand
BDBM50601469
Substrate
n/a
Meas. Tech.
ChEMBL_2237091 (CHEMBL5150987)
IC50
10.0±n/a nM
Citation
 Robello, M; Barresi, E; Baglini, E; Salerno, S; Taliani, S; Settimo, FD The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities. J Med Chem 64:3508-3545 (2021) [PubMed] 
Target
Name:
Group IIE secretory phospholipase A2
Synonyms:
PA2GE_MOUSE | Pla2g2e
Type:
PROTEIN
Mol. Mass.:
15949.46
Organism:
Mus musculus
Description:
ChEMBL_489275
Residue:
142
Sequence:
MKPPIALACLCLLVPLAGGNLVQFGVMIERMTGKPALQYNDYGCYCGVGGSHWPVDETDWCCHAHDCCYGRLEKLGCDPKLEKYLFSITRDNIFCAGRTACQRHTCECDKRAALCFRHNLNTYNRKYAHYPNKLCTGPTPPC
  
Inhibitor
Name:
BDBM50601469
Synonyms:
CHEMBL5172164
Type:
Small organic molecule
Emp. Form.:
C26H22N2O5
Mol. Mass.:
442.4633
SMILES:
Cc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O
Structure:
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