Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50354136
Substrate
n/a
Meas. Tech.
ChEMBL_770824 (CHEMBL1837629)
IC50
>10000±n/a nM
Citation
 Cichero, E; Ligresti, A; Allarà, M; di Marzo, V; Lazzati, Z; D'Ursi, P; Marabotti, A; Milanesi, L; Spallarossa, A; Ranise, A; Fossa, P Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor. Eur J Med Chem 46:4489-505 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50354136
Synonyms:
CHEMBL1836121
Type:
Small organic molecule
Emp. Form.:
C26H28N2O4
Mol. Mass.:
432.5115
SMILES:
CCOC(=O)C(=C\c1cn(CCN2CCOCC2)c2ccccc12)\C(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: