Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50359687
Substrate
n/a
Meas. Tech.
ChEMBL_792210 (CHEMBL1930737)
Ki
0.21±n/a nM
Citation
 Ferorelli, S; Abate, C; Pedone, MP; Colabufo, NA; Contino, M; Perrone, R; Berardi, F Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities ass¿? receptor ligands. Bioorg Med Chem 19:7612-22 (2011) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50359687
Synonyms:
CHEMBL1929279 | CHEMBL1929431
Type:
Small organic molecule
Emp. Form.:
C18H29NS
Mol. Mass.:
291.495
SMILES:
CC1(C)CCCN(CCCC2CCCc3sccc23)C1
Structure:
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