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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50408910
Substrate
n/a
Meas. Tech.
ChEMBL_139918 (CHEMBL748586)
EC50
85.11±n/a nM
Citation
 Botero Cid, HM; Tränkle, C; Baumann, K; Pick, R; Mies-Klomfass, E; Kostenis, E; Mohr, K; Holzgrabe, U Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically. J Med Chem 43:2155-64 (2000) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51688.65
Organism:
Pig
Description:
Cholinergic, muscarinic 0 GUINEA PIG::P06199
Residue:
466
Sequence:
MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRIVKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50408910
Synonyms:
CHEMBL2111531
Type:
Small organic molecule
Emp. Form.:
C46H56N4O2
Mol. Mass.:
696.9613
SMILES:
C[N+](C)(CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2\C1=C\c1ccccc1)CCCN1C(=O)c2ccccc2\C1=C\c1ccccc1
Structure:
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