Reaction Details Report a problem with these data
Target
Neuraminidase
Ligand
BDBM50016374
Substrate
n/a
Meas. Tech.
ChEMBL_1347422 (CHEMBL3267841)
IC50
1.8±n/a nM
Citation
 Chen, CL; Lin, TC; Wang, SY; Shie, JJ; Tsai, KC; Cheng, YS; Jan, JT; Lin, CJ; Fang, JM; Wong, CH Tamiphosphor monoesters as effective anti-influenza agents. Eur J Med Chem 81:106-18 (2014) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50016374
Synonyms:
CHEMBL3263938
Type:
Small organic molecule
Emp. Form.:
C22H35N2O5P
Mol. Mass.:
438.4975
SMILES:
CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)P(O)(=O)OCCCc1ccccc1 |r,c:7|
Structure:
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