Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM60985
Substrate
n/a
Meas. Tech.
ChEMBL_1460336 (CHEMBL3370491)
Ki
510000±n/a nM
Citation
 Martin, DP; Blachly, PG; McCammon, JA; Cohen, SM Exploring the influence of the protein environment on metal-binding pharmacophores. J Med Chem 57:7126-35 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM60985
Synonyms:
1-hydroxy-2-pyridinethione | 1-hydroxypyridine-2-thione | 1-oxidanylpyridine-2-thione | MLS001335994 | SMR000814708 | cid_1570
Type:
Small organic molecule
Emp. Form.:
C5H5NOS
Mol. Mass.:
127.164
SMILES:
On1ccccc1=S
Structure:
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