Affinity DataKi: 0.00250nMAssay Description:Binding affinity towards Adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Binding affinity towards Adenosine deaminaseMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Pseudomonas aeruginosa)
University of Illinois
University of Illinois
Affinity DataKi: 500nMAssay Description:In order to find new inhibitors, we carried out in silico screening of AaIspH and EcIspH using ZINC and National Cancer Institute (NCI) libraries and...More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:In order to find new inhibitors, we carried out in silico screening of AaIspH and EcIspH using ZINC and National Cancer Institute (NCI) libraries and...More data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Escherichia coli (Enterobacteria))
University of Illinois
University of Illinois
Affinity DataKi: 3.00E+3nMAssay Description:In order to find new inhibitors, we carried out in silico screening of AaIspH and EcIspH using ZINC and National Cancer Institute (NCI) libraries and...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 6.40E+4nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+5nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 5.10E+5nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+5nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+5nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+6nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+6nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of California At San Diego
Curated by ChEMBL
University Of California At San Diego
Curated by ChEMBL
Affinity DataIC50: 0.0740nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of California At San Diego
Curated by ChEMBL
University Of California At San Diego
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of California At San Diego
Curated by ChEMBL
University Of California At San Diego
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of California At San Diego
Curated by ChEMBL
University Of California At San Diego
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of California At San Diego
Curated by ChEMBL
University Of California At San Diego
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 31nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 36nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 41nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 43nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrateMore data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 68nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 119nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 133nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 138nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human Cathepsin V using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 156nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 164nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 205nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 210nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
TargetTuberculosinyl adenosine transferase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 210nMAssay Description:For inhibition assay of Rv3378c, using tuberculosinyl diphosphate and adenosine as substrates, a mixture of 100 µM TPP, 100 µM adenosine,75 µg/mL Rv3...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair